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Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...How to be ‘appy’ on call: a brief guide to mobile phone applications for the on-call ophthalmologist
One of the unexpected outcomes of the COVID-19 pandemic has been an increased reliance and integration of computer technology within hospital medicine. The need for stricter infection control policies during and after lockdown has seen a boom in technology utilisation....From dry eyes to glaucoma: How the menopause impacts your eyes and what to do about it, according to an optician
Menopause, much like entering puberty, comes with hormonal disruptions that change a woman's body and behaviour. Some of the first visible side effects are hot flushes, weight gain, and acne, accompanied by behavioural symptoms like mood swings, insomnia, and brain...
Diabetic polyneuropathy and risk of developing diabetic retinopathy
Diabetic polyneuropathy (DPN), diabetic retinopathy (DR) and diabetic nephropathy are widely classified as microvascular complications of diabetes. DPN, which may cause complete sensation loss, is another common complication of DM. The DPN-related diminished sensation presents a significant risk factor for...Conference Report: Building on a successful 2024: A week of learning at the Kabgayi Eye Unit
2024 was an exceptional year for us at Kabgayi Eye Unit (KEU). We hosted Rwanda’s first-ever international ophthalmology conference, established the Kabgayi Learning and Simulation Centre (KLAS) – a dedicated wet lab and skills transfer centre, and launched our training...
Risk of developing pseudotumor cerebri in women using a levonorgesteral intrauterine device
Pseudotumor cerebri (PCT) is a disorder causing increased intracranial pressure without a mass lesion, usually seen in obese women of childbearing age. Idiopathic intracranial hypertension is an idiopathic form of the disorder, but several medications have been associated with the...University of Gloucestershire launches first of its kind ophthalmic imaging degree
Ophthalmic science is a dynamic and constantly evolving profession, with ophthalmic imagers / technicians fundamental to the smooth and efficient running of ophthalmology departments. Traditionally, as the role has developed, ophthalmic imagers have come from a variety of backgrounds, finding...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
Congenital aniridia with or without retinal detachment
The authors present the clinical and molecular genetic evaluations performed on a large Iranian pedigree with 26 aniridia affected patients in four generations and some with retinal detachment. Members of the family affected with aniridia were invited to participate after...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
