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Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis

Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...

Patterns of binocular diplopia in giant cell arteritis (GCA)

Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...

Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders

This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...

The Lancet Global Health Commission on Global Eye Health: vision beyond 2020

Introduction The Lancet Global Health Commission on Global Eye Health was published in 2021 [1]. Drawing on expertise from within and outside the eye health sector, the Commission set out to: inform governments and other stakeholders about the path forward...

Artificial intelligence and oculomics: Improving global health

The application of artificial intelligence (AI), and in particular deep learning, to high-resolution ocular imaging has led to many new discoveries, enabling the prediction of multiple different systemic diseases from ocular biomarkers. This emerging field is known as ‘oculomics’ [1]....

What’s Eating Gilbert Pete

“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...

SOS (Simplified Ophthalmic Statistics) Part 3: Which statistical test should I use (if any)?

P<0.05 is a statement that brings joy to many researchers. Arguably this is because inclusion of such a statement may increase the chance of acceptance for publication. Whilst statisticians and non-statisticians are united in trying to change this culture, cultural...

My Top Five: Emerging technologies revolutionising ophthalmology

Advancements in ophthalmology have significantly transformed eyecare practices. This article explores five emerging technologies that are revolutionising the field, from virtual reality (VR) surgical training to novel therapies for corneal conditions. These innovations are reshaping how eyecare professionals diagnose, treat...

A career in uveitis

As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...

Insights on medical AI for ophthalmology: an update on current perspectives

Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...

Patient care a family affair at Newcastle-Under-Lyme eye hospital

With Mother’s Day just around the corner, mother and daughter Lisa Moors and Hannah Young won’t have to wait until next Sunday to spend time together - the pair work side-by-side, caring for hundreds of cataract surgery patients each week...

World Diabetes Day workshop highlights the importance of education to protect the sight of people living with diabetes

Health professionals from all over the world came together to mark World Diabetes Day on 14 November 2022 through an online workshop celebrating progress in development of diabetic retinopathy (DR) services in low-and middle-income countries (LMICs).