Journal Reviews

Ophthalmologica journal cover image.

Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders

3 February 2023 | | Retina / Uvea / Vitreous | Aflibercept, Anti-VEGF, Dexamethasone implant, Diabetic macular oedema, Persistent, Ranibizumab, Resistant

This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...

Ophthalmologica journal cover image.

Effect of syringe-filling technique and risk for endophthalmitis after intravitreal injection of anti-VEGF agents

2 August 2022 | | Retina / Uvea / Vitreous | Aflibercept, Anti-vascular endothelial growth factor, Bevacizumab, Endophthalmitis, Filling, Prefilled syringe, Ranibizumab, Syringe

In this retrospective study the authors compare the risk for post-injection endophthalmitis between different anti-vascular endothelial growth factor (VEGF) agents and syringe preparation technique. This multicentre study included 197,402 injections. The drugs included in this study were three Anti-VEGF agents...

Aflibercept treatment in polypoidal choroidal vasculopathy

1 April 2019 | | Retina / Uvea / Vitreous | Aflibercept, Caucasian population, Indocyanine green angiography, Optical coherent tomography, Polypoidal choroidal vasculopathy, Prospective study

The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...