Journal Reviews

Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis

1 December 2022 | | Neuro-Ophthalmology | Optic neuritis, axonal degeneration, neurofilament protein, retina, tissue

Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...