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Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema

Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...

G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

Could idebenone by the solution for treating dominant optic atrophy?

Dominant optic atrophy (DOA) is a disease of the retinal ganglion cells, with no current treatment options. In most cases, DOA is caused by a mutation in the OPA1 gene. The aim of this study was to evaluate the effect...

Impact of initial management on relapse in Vogt–Koyanagi–Harada syndrome

In this retrospective, multi-centre, observational study, the impact of the initial management of Vogt-Koyanagi-Harada syndrome (VKHS) was assessed by reviewing the records of all patients diagnosed with VKHS between January 2001 and December 2020 in two French tertiary centres, with...

Do patient demographics influence AMD clinic attendance during COVID-19 lockdown?

The authors assess the impact of the COVID-19 pandemic on adherence to scheduled clinic appointments among age-related macular degeneration patients in a clinic in North Wales. The COVID-19 pandemic has significantly affected the population, affecting economic and social wellbeing, whilst...

VISION 2020 LINKS: Retinoblastoma 
in Africa

The VISION 2020 LINKS Programme is part of the ‘VISION 2020: The Right to Sight’ global initiative to eliminate avoidable blindness [1]. The LINKS Programme works with overseas eye departments to help identify priorities and match their priority needs with...

Cancer associated retinopathy

Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...

Feb/Mar 2016 Quiz 2

History A 30-year-old male presents with a phthisical left eye and undergoes enucleation. He has some lesions in his right eye that are under ophthalmic surveillance. Figure 1 is a low power of the enucleation. Figures 2, 3 and 4...

An ophthalmology elective in Kandy, Sri Lanka

On my first day at The Centre for Sight, Kandy General Hospital, I observed an enucleation. The surgeons worked with quiet precision, preserving the extraocular muscles for prosthesis placement. But when the time came, it became clear that the prosthesis...

Optical coherence tomography – reinventing the eye examination

It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...

Grading of ocular inflammation in uveitis: an overview

Anterior uveitis is the commonest form of uveitis, which can lead to severe morbidity if not treated appropriately [1]. Data from general ophthalmology practices suggest around 90% of uveitis encountered by comprehensive ophthalmologists is anterior uveitis [2]. Intermediate (vitreous), posterior...

Ophthalmic mentors: Professor Sir Peng Tee Khaw

In the second of our interviews in this series, Eye News speaks to Professor Sir Peng Tee Khaw, Professor of Glaucoma and Ocular Healing, Consultant Ophthalmic Surgeon, Director of the National Institute for Health Research, Biomedical Research Centre at Moorfields...