You searched for "retinal"
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
1 October 2019
| Sofia Rokerya
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EYE - Vitreo-Retinal
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
Pathological myopia: a trainer’s perceptive
3 April 2024
| Anitha Priya Arun Shankar, Adelehin Ijasan
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EYE - Vitreo-Retinal
High myopia is defined as myopic refraction of greater than -6 dioptres with an axial length greater than 26.5mm, while pathological myopia is myopic refraction with posterior pole degeneration [1]. These degenerative changes can affect a young population and in...
Variability between handheld fundus cameras
3 January 2025
| Nishita Patel
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EYE - Glaucoma
Handheld fundus cameras offer the potential of enhancing opportunities for telemedicine diagnosis of glaucoma, especially in underserved settings, as they are less bulky, inexpensive and don’t require skilled personnel compared to traditional table-mounted retinal cameras. This study aimed to compare...
Amblyopia OCT results
The authors compared the macular and peripapillary retinal nerve fibre layer (RNFL) thicknesses of amblyopic and fellow eyes using Stratus optical coherence tomography (OCT) to reveal any differences. They sought to determine the anatomical differences between these subtypes of strabismic...Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management
1 December 2016
| Antonio Berarducci, Tom Williamson
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EYE - Vitreo-Retinal
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...
Vitreoretinal Disease: Diagnosis, Management and Clinical Pearls (second edition)
A comprehensive, well-illustrated and highly informative resource providing excellent descriptions of vitreoretinal diseases, their presentation, diagnosis and management. The 40 chapters are grouped into four sections, namely: the Anatomy and Physiology of the vitreous, retina, choroid and retinal pigment epithelium;...Pathophysiology of diabetic macular oedema: why combination therapy may be better
1 October 2015
| Winfried MK Amoaku
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EYE - Vitreo-Retinal
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...
The blue-light hazard – is it true?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: The blue-light hazard – is it true? Blue light is part of the visible optical spectrum...
Vision loss during Eylea treatment for AMD
1 December 2017
| Saruban Pasu
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EYE - Vitreo-Retinal
This report investigated patients who lost more than two lines of vision despite periodic injections of aflibercept and explored the factors associated with vision loss. One hundred and ninety-six eyes were included in this study over a two year period....
SLT short-term results
1 June 2014
| Lorraine North
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EYE - Glaucoma
The aim of the study was to evaluate the risk of adverse effects and short-term results after 360 degrees selective laser trabeculoplasty (SLT) in glaucoma patients. The authors enrolled 64 eyes of 64 patients all who had poorly controlled primary...
RTP801 as a neuroprotective and axon regenerative treatment
1 April 2016
| Wai Siene Ng
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EYE - Neuro-ophthalmology
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
