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My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Technology in ophthalmology – a promising future and what we need to know about the regulations

1 October 2017 | | EYE - Cataract, EYE - Refractive, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Orbit, EYE - Vitreo-Retinal, EYE - General
Undoubtedly, ophthalmology is one of the greatest sources of inspiration for technological progress in medicine. Thus far, we have seen remarkable advancements in the technology used by ophthalmologists across all subspecialties. From simplifying common procedures, to treating previously incurable conditions,...

Caring for adults with an ocular tumour

1 December 2015 | | EYE - Vitreo-Retinal
Detection If you screen for an intraocular tumour, dilate the pupil. If the patient is driving, use phenylephrine only. If the patient declines, document this in the casenotes. Don’t forget to look for sentinel vessels, which would indicate a ciliary...

What's trending Oct/Nov 2021

1 October 2021 | | EYE - Cataract, EYE - Refractive, EYE - Vitreo-Retinal, EYE - General
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #cataracts #holography #simulation Cataracts are the major cause of blindness globally and innovating novel management strategies remains as important as ever...

A patient report of pseudoxanthoma elasticum, angioid streaks and choroidal neovascularisation

1 October 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) on their own do not cause many problems, with the majority of patients remaining asymptomatic [1]. However, once choroidal neovascularisation (CNV) occurs, the visual prognosis of the patient rapidly declines [2]. Treatment is imperative to try and...

The approach to trabeculectomy postoperative complications

1 August 2016 | | EYE - Glaucoma
Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...

Specialty-driven EMR for paperless clinical environment – insights for an informed choice

1 August 2016 | | EYE - General
Deployment of specialty-driven (or specialty-specific) electronic medical record (EMR) systems across UK ophthalmology units appears to be growing rapidly at the expense of generic, multiuse digital technology packages. Experience further suggests that open source systems can play a significant role...

Celebrating eight years of the nurse-led intravitreal injection service

4 February 2021 | | EYE - Vitreo-Retinal, EYE - General
Moorfields Eye Hospital NHS Foundation Trust in London celebrated the eighth year of its nurse-led intravitreal (IVT) injection service in 2020. In collaboration with Beaver-Visitec International (BVI), Moorfields’ comprehensive one-day course for non-medical staff has blossomed into a thriving success....

An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

5 April 2022 | | EYE - Cornea, EYE - General
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

Ophthalmic mentors: Professor Carrie MacEwen

1 February 2015 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Caroline (Carrie) MacEwen is a Consultant Ophthalmologist at Ninewells Hospital and Medical School, Dundee, and Head of the Ophthalmology Department at the University of Dundee (Honorary Professor). She trained in Glasgow, Dundee and London. Carrie took over as President of...