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CVI features in an Indian population

This study describes the predisposing factors and ophthalmic characteristics of children with cortical visual impairment (CVI) at a tertiary centre in India. This was a retrospective cross-section study of children <16-years-old over a four-year period. A review of 88 patients...

Clinical features of ocular syphilis

The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...

Lagophthalmos as a potential complication of COVID-19

Lagophthalmos is a condition associated with the inability to close the eyelids effectively, with the main cause being facial nerve palsy. The authors aimed to investigate whether lagophthalmos was associated with coronavirus infection (COVID-19) by comparing patients diagnosed with lagophthalmos...

Paediatric emergency presentations in an urban centre

The authors aimed to evaluate aetiologies in paediatric patients presenting to the Wills Eye Emergency department (USA) with particular emphasis on trauma. This was a retrospective review of one-year hospital data; 1136 paediatric patients, 57.4% male, 50.7% white, 36.8% black,...

Choroid and retinal changes post COVID-19

The authors aimed to evaluate choroid and inner neural layers in people previously recovered from Covid-19 compared to healthy controls using optical coherence tomography (OCT) over a six-month period. They recruited 96 people: 56 with Covid-19 at least three months...

Adjunct amniotic membrane during enucleation for retinoblastoma to prevent implant exposure

Amniotic membrane (AM) has potential for treatment of retinoblastoma (RB) patients with contracted sockets after enucleation. The authors present their experience of AM with enucleation for patients with RB after chemotherapy in this retrospective study of 100 eyes of 107...

Steroid implants in the treatment of post-epiretinal membrane peel macular oedema

This is a retrospective review of 39 eyes of 37 patients treated with Ozurdex® (intravitreal dexamethasone implant) for persistent post-operative cystoid macular oedema (CMO) following vitrectomy and idiopathic epiretinal membrane (ERM) peeling. The 0.7mg implant was injected in each eye...

Transfected RPE cells inhibit AMD in rats

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...

Effect of topical diclofenac on postoperative PRK pain: RCT

A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...

Aqueous humour cytokine levels in PCV and nAMD

This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...