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G-CSF intravitreal injections for NAION: a pilot study
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...
SS-OCT assessment of ITC after phacoemulsification
This is a multicentre randomised controlled trial of 22 patients with primary angle closure glaucoma with peripheral anterior synechia and peripheral primary angle closure glaucoma (PACG) with peripheral anterior synechia (PAS) detected by indentation gonioscopy was randomised into two groups....
Changes in ocular biomarkers in Vogt-Koyanagi-Harada disease after pulse steroid therapy
This retrospective study aimed to evaluate the early and chronological changes in ocular biomarkers in patients of Vogt Koyanagi Harada (VKH) disease who received pulse steroid therapy. It further aimed to identify which biomarkers correlated with the best corrected visual...Trends in Ophthalmology Meeting 2024
The ‘Trends in Ophthalmology’ meeting has been organised annually by the Ophthalmology faculty of St Thomas’ Hospital for almost 50 years. It highlights ‘trends’ in ophthalmic management and covers a wide range of ophthalmic sub-specialties which alternate every 2 years....Mainline Instruments - Pentacam Educational Day
Mainline Instruments - Pentacam® Educational DayAspiration of anteriorly migrated dexamethasone implant using an 18G intravenous cannula
Intravitreal dexamethasone (Ozurdex 0.7mg) is a biodegradable, sustained-release implant used to manage diabetic macular oedema, macular oedema secondary to retinal vein occlusion, and non-infectious posterior uveitis due to its anti-inflammatory effects and VEGF suppression [1]. While effective, the implant may...“Beware of the pigment”
Using some captivating artwork, Iheukwumere Duru describes key features of pigment dispersion syndrome. Pigmentary dispersion syndrome (PDS) leads to pigmentary glaucoma (PG) in approximately 35-50% of patients with the condition [1]. PG is the leading cause of non-traumatic blindness in...
Cutaneous malignant melanoma metastasis to pseudophakic lens
Metastases to the eye and orbit are rare and intraocular cutaneous malignant melanoma metastasis (ICMM) is exceedingly rare, representing around 5%. There have only been three previous cases of ICMM to the lens in the literature, all of which presented...
Conservative vs surgical management outcomes for congenital fibrovascular pupillary membrane for young vs older children
The authors present the clinical characteristics and outcomes of different treatment methods for congenital fibrovascular pupillary membrane (CFPM). This was a retrospective case series from a single centre including 12 patients (13 eyes; 4 males, 8 females) over a 7-year...
Posterior circulation stroke associated demographics, risk factors and aetiology
The authors present a retrospective case notes review of patients diagnosed with homonymous hemianopia following a radiologically confirmed stroke. A total of 85 patients were identified by searching an electronic medical records system over an 11-year period. Data were extracted...It’s not always GCA
Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...
