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My Top Five: Emerging alternatives to manage and treat nAMD

3 April 2024 | | EYE - General
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

My ophthalmology elective: Reflections from Singapore

4 August 2025 | | EYE - General
Why do an ophthalmology elective? An elective in ophthalmology can offer a unique opportunity to delve deeper into the highly competitive specialty beyond the confines of the medical school curriculum, while experiencing a healthcare system in a new cultural setting....

“Steel True, Blade Straight”

1 October 2019 | | EYE - General
Steven Kerr of the Royal College of Surgeons of Edinburgh explores the medical career of Arthur Conan Doyle, his relationship with his mentor Joseph Bell and his fascination with ophthalmology. Arthur Ignatius Conan Doyle was born in Edinburgh on the...

Crystalline keratopathy in monoclonal gammopathy of undetermined significance

2 April 2025 | | EYE - Cornea
Monoclonal gammopathies encompass a group of plasma cell disorders characterised by the excessive production of abnormal monoclonal immunoglobulins in the bloodstream [1]. This category includes multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), amyloidosis and other lymphoproliferative disorders. Monoclonal gammopathy...

Simulating the visual impairment symptoms of age-related macular degeneration in virtual reality

5 June 2023 | | EYE - Vitreo-Retinal
A new virtual reality application visually simulates age-related macular degeneration and demonstrates its progression over time including some Charles Bonnet syndrome hallucinations. Introduction Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries with the prevalence of...

Paediatric optic disc anomalies

4 December 2025 | | EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Paediatrics
Anomalies of the optic nerve are relatively rare, but account for a significant proportion of sight impairment in children and adults. The recognition of these anomalies by eye health professionals is important not only due to their potential impact on...

Strategies for managing neovascular AMD and DMO in routine clinical care

1 October 2015 | | EYE - Vitreo-Retinal
Treatment practice in the management of neovascular age-related macular degeneration (AMD) and diabetic macular oedema (DMO) illustrate increasing adoption of patient-tailored treatment approaches based on initial diagnosis and regular monitoring of imaging and visual outcomes in routine clinical care. The...

A paradigm shift in the way we approach cataract surgery

1 February 2015 | | EYE - Cataract, EYE - Refractive
Cataract surgery is the most common elective surgical procedure in the UK [1], with in the region of 350,000 cases being conducted each year. With an ageing population, this figure will only continue to rise over time. Cataract surgery is...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...