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PRPF31-related retinitis pigmentosa and asymptomatic carriers

The authors present a study of 21 patients with variants in the PRPF31 gene classified as pathogenic or likely pathogenic. These variants are caused by autosomal dominant retinitis pigmentosa (RP-11). Between January 2020 and November 2021 patients underwent tests of...

Septo-optic dysplasia – a case note review

Septo-optic dysplasia (SOD) is a congenital disorder belonging to the midline brain malformation group. The condition manifests as a classical triad, including optic nerve hypoplasia (ONH), agenesis of midline structures (absent septum pel-lucidum and agenesis of the corpus callosum), and...

Predicting outcome for visual acuity in optic neuritis associated with multiple sclerosis

The authors present a retrospective cohort study to evaluate key predictors of long-term high-contrast visual acuity following optic neuritis associated with multiple sclerosis. All patients coded as optic neuropathy and assessed by a neuro-ophthalmologist over a 10-year period were screened...

Features of bacterial orbital cellulitis on MRI imaging

This multi-centre retrospective study from Australia and the UK examined the quantitative and qualitive parameters of magnetic resonance imaging (MRI) imaging in bacterial orbital cellulitis. Twenty MRI scans from 20 patients with pre-septal and orbital fat involvement (mean age: 40.8...

Improvement of visual acuity with dichoptic training for amblyopia

This study evaluated the effectiveness of dichoptic amblyopia treatment using the Bynocs AmblyGo programme in reversing various types of amblyopia in a retrospective cohort. At recruitment, all patients had demonstration of the treatment. Patients continued treatment at home via internet-connected...

Selective laser trabeculoplasty after medical treatment

Selective laser trabeculoplasty (SLT) is a well-established treatment for open-angle glaucoma (OAG) and ocular hypertension (OHT). This post-hoc secondary analysis of the LiGHT trial extension examined SLT as a secondary intervention after 3 years of protocolised medical therapy in patients...

Saving sight and changing lives: working with Syrian refugees in Jordan

Two ophthalmologists from the Emory Eye Center share their three-year experience of treating refugees in the camps in Jordan. Jordan currently hosts an estimated 1.4 million Syrian people who have fled the war in their home country. Cataract & Cornea...

My Top Five: Innovations in the diagnosis of ocular tumours

Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

Ophthalmic viscoelastic devices: Useful insights for a novice cataract surgeon

Ophthalmic viscoelastic devices (OVDs) are essential in many different stages of cataract surgery. This article discusses the categories of OVDs and their respective properties, and highlights their uses in different scenarios faced in cataract surgery. Ophthalmic viscoelastic devices are gel-like...

The Escape Room and gamification of ophthalmology teaching

Recently, there has been an interesting development in medical education and its ‘gamification’. Educators are constantly looking for new ways to engage their students by adding a friendly element of competition, as evidenced by the great success of online education...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Minimally Invasive Glaucoma Surgery: What options are there and when might they be considered?

In recent years there has been a rapid expansion in a group of operations termed ‘minimally invasive’ or ‘micro invasive’ glaucoma surgery (MIGS). These options generally offer less significant IOP reduction, but with a more favourable safety profile when compared...