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Breakthroughs in the genetics of angle-closure glaucoma

Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Ophthalmic viscoelastic devices: Useful insights for a novice cataract surgeon

Ophthalmic viscoelastic devices (OVDs) are essential in many different stages of cataract surgery. This article discusses the categories of OVDs and their respective properties, and highlights their uses in different scenarios faced in cataract surgery. Ophthalmic viscoelastic devices are gel-like...

Aqueous misdirection: a case series of unexpected surgical complications

Aqueous misdirection (AM), also known as malignant glaucoma, is a form of secondary glaucoma that typically presents with shallowing of the anterior chamber (AC), raised intraocular pressure (IOP), and reduced visual acuity (VA) in the presence of patent peripheral iridotomies...

Collaborating across the Caribbean to tackle diabetic retinopathy

The VISION 2020 LINKS Programme has been running since 2004, with a focus on improving the quality and quantity of eye care training in low-income countries [1]. In 2014, the Diabetic Retinopathy Network (DR-NET) was established [2]. This is a...

A career in uveitis

As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...

Uveal melanoma

Uveal melanoma is the most common primary intraocular tumour. However, they are still rare, with an incidence of 2-8 per million [1]. The presence of a choroidal naevus is a risk factor for uveal melanoma [1]. Patients with choroidal lesions...

Charity work in Cambodia: Culture, cataracts, and cruelty

Cambodia has one of the lowest numbers of eye specialist doctors per capita in the world, and Bita Manzouri takes us on a journey into the charitable work of the Khmer Sight Foundation who are working to combat this. “Ut...

My Top Five: Key insights from recent research into uveitis in adults

Uveitis, characterised by inflammation of the uvea – the eye’s middle layer comprising the iris, ciliary body, and choroid – remains a leading cause of visual impairment worldwide [1]. It primarily affects adults aged 20–50 years. Untreated uveitis may cause...

IN FOCUS - Prevention and treatment of blindness worldwide: the story of ‘VISION 2020: The Right to Sight’

The story of blindness and efforts to prevent and treat it cannot be told without going back to the earliest recorded history of blindness. Trachoma was described in ancient Egypt, cataract surgery in India about the fifth century BC and...

The approach to trabeculectomy postoperative complications

Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...

The embryology of the eye

Nobody claims to like embryology. At least nobody I know. It has been a neglected part of the curriculum since time immemorial and a vicious cycle occurs in which those with an incomplete understanding fail to appreciate the inherent beauty...

A missed intraocular telescope – an opportunity to re-focus the evidence

Intraocular telescopes allow magnification of the image so that it would be projected into a larger area of the macula, this makes the central defect caused by dry age-related macular degeneration (AMD) smaller. The most common approach is a Galilean...