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Building data infrastructure for eye research in the NHS: Real-world lessons from the Liverpool Eye Data Platform
The Liverpool Eye Data Platform demonstrates how governance-compliant infrastructure can bring together routinely-collected, siloed NHS eye data. Routine care delivered across the NHS generates vast amounts of clinical data within a healthcare system that is uniquely characterised by comprehensive population...The Complainers
There she was. Sitting in the waiting room with her arms crossed, tut-tutting to herself and shaking her head mournfully every few minutes. We gazed at her from a safe distance while one of the nurses confirmed what we already...Usher syndrome: an overview
Usher syndrome is the most common hereditary condition that affects both vision and hearing. It is an autosomal recessive condition characterised by retinitis pigmentosa (RP) and bilateral sensorineural hearing loss [1,2]. Usher syndrome is the cause of approximately 10% of...My Top Five: Innovations in the diagnosis of ocular tumours
Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...Regulatory drug evaluations and expedited review initiatives: EU and US perspectives
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...
Tumour deposits following choroidal melanoma treatment
The authors present the unique case of retinoinvasive melanoma following treatment of choroidal melanoma with brachytherapy. Uveal melanoma, the commonest intraocular malignancy in adults, presents as a pigmented mass in the choroid, ciliary body, or iris. A 79-year-old Caucasian male...Newer generation IOL platforms designed for high-quality visual performance after cataract surgery
Expanding intraocular lens (IOL) capabilities provide broadening options, ranging from next-generation monofocal IOLs for basic cataract surgery, to specialised premium IOLs for lens-based presbyopia correction and astigmatism correction at the time of cataract surgery. Rod McNeil considers several newer alternative...
