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Seminars in Ophthalmology journal cover image

Treat-and-extend regimen in treatment of patients with type 3 neovascularisation

5 October 2020 | | EYE - Vitreo-Retinal
Type 3 neovascularisation, also known as retinal angiomatous proliferation is a distinct subtype of neovascular AMD characterised by intraretinal neovascularisation. This retrospective study included 17 eyes diagnosed with type 3 neovascularisation who were changed from pro-re-nata (PRN) based treatment regime...

Lines, dots, spots and rings in ophthalmology: understanding eponyms

1 April 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Eponymous names are familiar to all who have undergone undergraduate and postgraduate training in medicine. The ability to name a few allows one to stand out among your peers and rare, or not so rare, eponymous syndromes are a favourite...

Paediatric optic disc anomalies

4 December 2025 | | EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Paediatrics
Anomalies of the optic nerve are relatively rare, but account for a significant proportion of sight impairment in children and adults. The recognition of these anomalies by eye health professionals is important not only due to their potential impact on...

Retinal pigment epithelium tears

1 June 2016 | | EYE - Vitreo-Retinal
In this paper the authors review the current knowledge of retinal pigment epithelium (RPE) tears. Although rare these can cause loss of visual acuity. They can occur spontaneously in pigment epithelial detachment (PED) due to occult choroidal neovascularisation (CNV), retinal...

Intravitreal aflibercept for retinal angiomatous proliferation (RAP)

2 December 2019 | | EYE - Vitreo-Retinal
In this prospective study the authors present the visual and anatomical outcome of patients with RAP lesions who were treated with intravitreal aflibercept. The study cohort of 46 patients reached study completion at week 96. They were all Caucasians, with...

Cavernous sinus syndrome

4 February 2021 | | EYE - Neuro-ophthalmology, EYE - General
Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...

Clinical relevance of the anatomic classification of neovascular age-related macular degeneration

1 February 2018 | | EYE - Imaging, EYE - Vitreo-Retinal
The author explains why an OCT-based classification of neovascular AMD is needed and how these neovascular subtypes may help to predict patients’ long-term visual outcome. Age-related macular degeneration (AMD) is a chronic and progressive neurodegenerative process involving the macula in...

The International Centre for Eye Health: weaving the global threads together

4 October 2023 | | EYE - General
The VISION 2020 LINKS & Networks Programme has been writing regular articles in Eye News about its capacity-strengthening activities in low- and middle-income countries (LMICs) for more than a decade. This, the first International Issue, is a landmark for Eye...

Pituitary tumours: why are they so often missed?

1 August 2017 | | EYE - Neuro-ophthalmology
Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...

Neovascular AMD: fresh recommendations underline standards of best practice

1 December 2013 |
The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...

Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress

2 August 2024 | | EYE - General
Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...

Discussing treatment modalities for bilateral wet AMD

1 December 2014 | | EYE - Vitreo-Retinal
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....