Journal Reviews
Microsporidia-induced stromal keratitis: a new cause of presumed immune stromal (interstitial) keratitis
This is a non-comparative retrospective observational case series from India from 1 October 2020 to 31 January 2021. The inclusion criteria were: (1) presence of nummular / coin shaped lesions with at least one >2mm in size and / presence...
Differentiating orbital cellulitis from non-specific orbital inflammation
This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...
High rate of conversion from ocular hypertension (OH) to glaucoma (UG) in subjects with uveitis
This is a retrospective study from Auckland over a 10-year period including 188 eyes of 139 subjects with either OH or UG and were included for analysis with a mean follow-up of 9.9 years. The most common uveitis causes were...
Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases
This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...
High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis
This is a retrospective study from Auckland over a 10-year period. A total of 188 eyes of 139 subjects with either ocular hypertension (OH) or uveitic glaucoma (UG) were included for analysis with a mean follow up of 9.9 years....
Management of ocular surface disease
This is a retrospective study of patients with ocular surface disease (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease), active...
Inflammation and microvascular changes in diabetic retinopathy
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
A novel way to distinguish between types of anterior ischaemic optic neuropathy
The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...
Topical nonsteroidal ant-inflammatory drugs (NSAIDs) in patients undergoing cataract surgery
Inflammation is a major risk factor for the development of cystoid macular oedema (CMO) after cataract surgery, leading to breakdown of the blood-retina barrier. There is a correlation between severity of CMO and level of postoperative inflammation. Laser flare meter...
Cutaneous malignant melanoma metastasis to pseudophakic lens
Metastases to the eye and orbit are rare and intraocular cutaneous malignant melanoma metastasis (ICMM) is exceedingly rare, representing around 5%. There have only been three previous cases of ICMM to the lens in the literature, all of which presented...
Orbital manifestations of granulomatosis with polyangitis
This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15...
IOP in children with uveitis
This is a retrospective study of paediatric uveitis (<16-years-old) between July 2002 to June 2016 of a total of 320 children from a single centre: 17.2 % (55/320 patients) developed raised IOP requiring therapy; 11.5% of eyes required glaucoma surgery...
