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Journal Reviews archive for 2016

Intravitreal bevacizumab vs. triamcinolone in patients with DMO at the time of cataract surgery

1 October 2016 | Anjali Gupta | EYE - Vitreo-Retinal

This prospective, single masked randomised control trial (RCT) compared visual and anatomical outcomes when either intravitreal bevacizumab (BVB) or triamcinolone (TA) was administered at the time of cataract surgery and at subsequent review, if required, in patients with diabetic macula...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

1 October 2016 | Bheemanagouda Patil | EYE - Vitreo-Retinal

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Retinal ganglion cell loss in diabetes and diabetic retinopathy

1 October 2016 | Anjali Gupta | EYE - Vitreo-Retinal

The aim of this observational case control study was to evaluate the association of diabetes and diabetic retinopathy (DR) with retinal ganglion cell loss. Cases were Chinese patients with type 2 diabetes with and without DR, aged 40-80 years. Eligible...

Paediatric uveitis in India

1 October 2016 | Saruban Pasu | EYE - Vitreo-Retinal

This article was a retrospective review of paediatric patients presenting to a tertiary hospital in India. Records over a three year period were reviewed. The authors highlight that children account for about 2.2-13.8% of uveitis patients and are at greater...

Prediction errors of formulas in optical biometers

1 October 2016 | Sharmina Khan | EYE - Cataract, EYE - Refractive

This study was conducted retrospectively in a private practice setting. Nine formulas were compared for prediction error (postoperative spherical equivalent (SE) minus, predicted SE calculated by each formula), using two optical biometers (Lenstar – optical low coherence reflectometry (OLCR) and...

OVD influences

1 October 2016 | Sharmina Khan | EYE - Cataract, EYE - Refractive

This prospective case series provides data on a previously uninvestigated area. Eyes due to have routine phakoemulsification were divided into six groups according to ophthalmic viscosurgical device (OVD) type. After cataract extraction aphasic refraction using intraoperative aberrometry with the ocular...

5-FU vs. Avastin as adjunct to conjunctival autograft

1 October 2016 | Sofia Rokerya | EYE - Cornea, EYE - General

The authors compare the outcome of pterygium treatment using 5-fluorouracil as an adjunct to free conjunctival autograft versus bevacizumab (Avastin) as an adjunct to free conjunctival autograft, via a randomised controlled prospective study. Seventy eyes of 70 patients were included...

Oral azithromycin for meibomian gland disease

1 October 2016 | Anjali Gupta | EYE - Cornea, EYE - General

Oral tetracyclines have been the traditional systemic treatment of blepharitis and acne rosacea, through inhibiting bacterial lipase production and reducing fatty acids. However, tetracyclines have a number of adverse side-effects and are required to be taken for a long duration...

C-spp corneal consequences

1 October 2016 | Jonathan Chan | EYE - Cornea, EYE - General | Cornea

This is a retrospective review of microbiological records of 22 patients, who had presented at the LV Prasad Eye Institute, India, between June 2009 and December 2012. The corneal scrapings were performed in all patients and had yielded significant growth...

Boston type I keratoprosthesis for limbal stem cell deficiency

1 October 2016 | Magdalena Popiela | EYE - Cornea, EYE - General

Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...

Bitemporal hemianopsia as a result of ethambutol toxicity

1 October 2016 | Claire Howard | EYE - Neuro-ophthalmology | Bitemporal, Mycobacterium, ethambutol, hemianopsia, toxicity

The authors present six cases of visual loss in patients treated with ethambutol for mycobacterium avium complex, including four patients with bitemporal hemianopsia. Two additional patients were undergoing glaucoma monitoring and developed visual field defects with ethambutol treatment, which recovered...

Case report of Leber hereditary optic neuropathy (LHON)

1 October 2016 | Claire Howard | EYE - Neuro-ophthalmology | Central scotoma, Leberhereditary optic neuropathy, macular hole

This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...

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