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Journal Reviews archive for 2014

Direct endoscopic probing for congenital lacrimal duct obstruction

1 April 2014 | Anjali Gupta | EYE - General

The most common treatment for congenital lacrimal duct obstruction (CLDO) is probing, which is traditionally a blind procedure. Previous literature reports success rates between 78-92%. The authors of this retrospective non comparative case series reviewed the success rates of probing...

PERG as a visual prognosticator in chiasmatic tumours

1 April 2014 | Anjali Gupta | EYE - General

Pattern electroretinogram (PERG) allows assessment of ganglion cell function and may therefore be used to assess anterior visual pathway dysfunction. This prospective non-randomised study assessed PERG before and after surgical removal of tumours in and around the sellar region compressing...

Macular slippage following macular hole surgery

1 April 2014 | Khadijah Basheer | EYE - General

The treatment of macular holes now involves peeling the internal limiting membrane (ILM) as well as vitrectomy and gas tamponade. It has been noted in previous studies that following an ILM peel the morphology of the macula is different. Tadayoni...

A relationship between central serous retinopathy and obstructive sleep apnoea

1 April 2014 | Khadijah Basheer | EYE - Vitreo-Retinal, EYE - General

This prospective study aimed to evaluate a relationship between central serous retinopathy (CSR) and obstructive sleep apnoea (OSA). Twenty-three subjects (six female and 17 male) were diagnosed with CSR and overnight polysonography was performed to record desaturation and apnoeic episodes....

New mouse model of diabetes mellitus

1 April 2014 | Graham Wallace | EYE - Vitreo-Retinal

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Autophagy in lens mitochondria loss

1 April 2014 | Graham Wallace | EYE - Cataract, EYE - Refractive | ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Long-term outcomes following surgery for traumatic cyclodialysis clefts

1 April 2014 | Nana Theodorou | EYE - General

This retrospective case series evaluated the long-term visual prognosis and intraocular pressure control following surgical treatment of traumatic cyclodialysis clefts. Cyclodialysis clefts result from the disinsertion of the longitudinal ciliary muscle fibres from the scleral spur and occur as a...

Pain score assessment in babies undergoing treatment for ROP

1 April 2014 | Nana Theodorou | EYE - General, EYE - Paediatrics, EYE - Strabismus

The aim of this study was to assess neonatal pain scores during laser treatment for retinopathy of prematurity (ROP) under sub-tenon anaesthetic with oral or rectal sedation. Sixty-two babies were included who have had ROP laser treatment over a seven...

Improved vision with perceptual learning

1 April 2014 | Carmel Noonan | EYE - General

This study examined whether the development of crowded near visual acuity can be stimulated and whether crowding effects can be reduced by perceptual learning. The authors compared a magnifier crowded task with a perceptual learning crowded task and perceptual learning...

Vision measurements vs. self-rating

1 April 2014 | Carmel Noonan | EYE - General

The aim of this study was to evaluate the association between self-rated vision status and tests of visual acuity, contrast sensitivity, stereoacuity, bilateral visual field and self-reported visual function in specific domains of near and far vision. The goal was...

Macular thickness and visual fields

1 April 2014 | Lorraine North | EYE - Glaucoma

The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...

Arterial stiffness and PEX

1 April 2014 | Lorraine North | EYE - Glaucoma

The authors describe a study of 25 newly diagnosed patients with pseudoexfoliation glaucoma (PEX) and 25 controls to evaluate carotid femoral pulse wave velocity (CF-PWV) values. The CF-PWV was assessed using a noninvasive device by measuring the pulse transmit time...

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