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Journal Reviews archive for 2016

Localising the cause of bloody tears

1 April 2016 | Claire Howard | EYE - Neuro-ophthalmology | Bloody, haemolacria, idiopathic, localization, plugs, punctal, tear

The authors present two cases of ‘idiopathic’ bloody tearing. The paper presents the potential causes of bloody tearing, highlighting the difficulty that can be encountered in diagnosing and managing these patients. The authors use punctal plugs in these cases which...

An unusual presentation of dysthyroid orbitopathy

1 April 2016 | Claire Howard | EYE - Neuro-ophthalmology | Gaze-evoked amaurosis, Optic neuropathy, Thyroid eye disease

The authors present a case of a 50-year-old male smoker who presented with bilateral gaze evoked amaurosis (GEA), i.e. the patient was aware of loss of vision in all gaze positions other than the primary position. The patient was being...

Bisphosphonates can cause orbital inflammation

1 April 2016 | Claire Howard | EYE - Neuro-ophthalmology | Bisphosphonate, complication, orbital inflammation, orbital inflammatory syndrome, side effect, zolendronate

The authors describe four patients with bisphosphonate induced orbital inflammation and review a further 25 cases in the literature. Intravenous zoledronate was the most common precipitant (76% of cases) with the mean time until onset of inflammation being three days...

Recurrent thyroid eye disease

1 April 2016 | James Hsuan | EYE - Neuro-ophthalmology

This study investigates the incidence of recurrent thyroid eye disease. The authors retrospectively reviewed the records of 415 patients who had been diagnosed with thyroid eye disease between 2006 and 2012. The medical notes were scrutinised for evidence of a...

Bupivicaine injection for Bell’s palsy

1 April 2016 | James Hsuan | EYE - Neuro-ophthalmology

This study assesses the use of intramuscular bupivicaine to treat lid retraction and lagophthalmos in facial palsy. It is a prospective non-comparative interventional series of 10 patients with Bell’s palsy (House-Brackman grade IV or V) who each received three serial...

RTP801 as a neuroprotective and axon regenerative treatment

1 April 2016 | Wai Siene Ng | EYE - Neuro-ophthalmology

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Association between serum levels of testosterone and estradiol with meibomian gland assessments in postmenopausal women

1 April 2016 | Wai Siene Ng | EYE - Oculoplastic, EYE - Orbit

This study aims to reveal any correlation between serum levels of testosterone and estradiol in postmenopausal women with meibomian gland dysfunction. Postmenopausal subjects were defined as amenorrhoea for at least one year with low follide stimulating hormone (FSH) and estradiol....

Ectopia lentis management

1 April 2016 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus

This review discusses the management of non-traumatic ectopia lentis in the paediatric population focussing on the variety of surgical options for these patients. The review considers visual sequelae and conservative management, limitations for surgery with respect to historical and current...

High myopia macular thickness

1 April 2016 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus

The purpose of this study was to compare macular thickness and volume in 15 highly myopic (>-6D) young children with 11 age-matched controls (-2 to +4D refractive errors) using Stratus third generation OCT. Mean spherical equivalent was -9.42 ±2.81D for...

Association of astigmatism and inferior oblique over action

1 April 2016 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus

The aim of this study was to evaluate the association between primary inferior oblique over action and astigmatism along the axis on the overacting muscle. The authors explored the postoperative change in axis of astigmatism and cylinder power in a...

Syndromic V-pattern management

1 April 2016 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus

The authors document their experience in the management of four cases of Crouzon syndrome and review the anatomical extraocular muscle anomalies noted during surgery. Horizontal strabismus surgery varied in each of the four cases according to individual extraocular muscle abnormalities...

Outcome of three to four muscle surgery for XT

1 April 2016 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus

This study evaluates the short-term outcomes of surgery involving three or four horizontal rectus muscles in patients with exotropia >40 prism dioptres. The authors evaluate the role of adjustable sutures and identify prognostic factors influencing surgical outcome. They assess the...

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