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Journal Reviews

Relationship between diabetic retinopathy and cerebrovascular reactivity changes

1 March 2024 | Claire Howard | EYE - Neuro-ophthalmology | Cerebral vasomotor reactivity, breath-holding index, diabetes mellitus, diabetic retinopathy, transcranial Doppler ultrasound

Cerebral micro-angiopathy caused by diabetes can manifest itself as an impairment in cerebrovascular reactivity. Transcranial doppler ultrasound (TCD) is a cost-effective and non-invasive way to measure the cerebrovascular reactivity. This study aimed to assess the relationship between the grade of...

BMJ Open Diabetes Research & Care journal cover image.

A scoping review of artificial intelligence tools for diabetic retinopathy in low- and middle-income countries

4 December 2023 | Elliott Taylor | EYE - Vitreo-Retinal | developing countries, diabetic retinopathy, information technology, public health

The authors conducted a scoping review to summarise the literature relating to artificial intelligence (AI) tools for diabetic retinopathy (DR) in low- and middle-income countries (LMICs). Eighty-one studies were included, following a comprehensive literature search. The majority of studies were...

Effect of heredity on risk of diabetic retinopathy

1 September 2023 | Kurt Spiteri Cornish | EYE - Vitreo-Retinal | Diabetic macular edema, heredity, proliferative diabetic retinopathy, risk factors, survival analysis

This study used survival analysis on 2199 patients who had reached vision-threatening diabetic retinopathy to investigate the contribution of heredity to diabetes together with other known risk factors for the development of either proliferative diabetic retinopathy (PDR) or diabetic macular...

Ophthalmologica journal cover image.

Morphological and functional outcome after subthreshold laser coagulation with a frequency-doubled Nd:YAG laser

2 August 2022 | Sofia Rokerya | EYE - Vitreo-Retinal | Central serous chorioretinopathy, Retinal imaging, Retinal laser coagulation

Central serous chorioretinopathy; Retinal imaging; Retinal laser coagulation

Inflammation and microvascular changes in diabetic retinopathy

1 February 2022 | Kurt Spiteri Cornish | EYE - Vitreo-Retinal | Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation

Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...

Progress in Retinal and Eye Research journal cover image.

Why is there subretinal fluid at the macula?

3 June 2021 | Zhihang Cheng | EYE - Vitreo-Retinal | Central serous chorioretinopathy (CSC), Differential diagnosis, Retinal disease, Serous fluid accumulation, Serous maculopathy

This is a review article looking at the differential diagnosis of subretinal fluid in the macula that could be diagnosed as central serous chorioretinopathy (CSCR). The authors have categorised them into 12 groups: neovascular diseases, vitelliform lesions, inflammatory diseases, ocular...

Ophthalmologica journal cover image

Correlation between aqueous flare and macular microvascular status in diabetes mellitus

7 April 2021 | Sofia Rokerya | EYE - Vitreo-Retinal | Aqueous flare, Diabetic retinopathy, Inflammation, Laser flare-cell meter, Microvascular injury, Optic coherence tomography angiography

The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...

Ophthalmologica journal cover image

Assessment of retinal capillary VD and FAZ area in CSC using OCTA

7 April 2021 | Sofia Rokerya | EYE - Vitreo-Retinal | Central serous chorioretinopathy, Optical coherence tomography, Optical coherence tomography angiography, Visual acuity

The authors aim to report a cross-sectional, case controlled study, the purpose of which was to access the retinal capillary vessel density (VD) and foveal avascular zone (FAZ) area in acute and chronic central serous chorioretinopathy (CSC) patients compared to...

Pupil responses in diabetes

4 February 2021 | Claire Howard | EYE - Neuro-ophthalmology | Diabetes mellitus, Diabetic retinopathy, dynamic pupillometry, pupil diameter, static pupillometry

This study aimed to investigate pupillary involvement in patients with type 2 diabetes mellitus (DM) and to evaluate any relationship between severity of diabetic retinopathy (DR) and pupillary responses. Participants included 133 individuals in four groups: proliferative DR (n=21), non-proliferative...

Two illustrative cases of AZOOR

1 February 2019 | Claire Howard | EYE - Neuro-ophthalmology | Acute zonal occult outer retinopathy, autofluorescence, ellipsoid zone, enlarged blind spot

The authors present two illustrative cases of acute zonal occult outer retinopathy (AZOOR) which causes acute idiopathic blind spot enlargement. The disease is characterised by sudden loss of outer retinal function associated with photopsia, with minimal or no fundoscopic changes...

A case series of acute visual loss following excessive alcohol and / or drug use

1 August 2015 | Claire Howard | EYE - Neuro-ophthalmology | Ophthalmoplegia, retinal artery occlusion, saturday night retinopathy

This study presents three cases of so called Saturday night retinopathy, an acute visual loss following intravenous drug abuse and stupor, leading to continuous pressure on the orbit while asleep. All three cases presented with acute vision loss and had...

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