Myopia in Han Chinese
2 February 2024
| Ian Reekie
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EYE - Cataract, EYE - Refractive
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Han Chinese, Myopia-associated genes, High myopia, retinal nervous system, single nucleotide polymorphisms
The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...
Internal limiting membrane (ILM) peeling on blood flow in diabetic macula
2 February 2024
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Diabetes, Epiretinal membrane, Inner limiting membrane, vessel density, vessel length density
This is a retrospective review of notes for diabetic patients with epiretinal membrane (ERM) who underwent surgery by the same surgeon. Nineteen had ERM peeling only, while the remaining 18 had both ERM and internal limiting membrane (ILM) peeling. The...
Characteristics of bilateral retinal detachment
4 December 2023
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Anatomic success rate, Bilateral retinal detachment, Buckle surgery, Fellow eye, Retinal symmetry, Vitrectomy
This was a retrospective study based at a tertiary centre which analysed the specific characteristics of bilateral Rhegmatogeous detachment, taken from the review notes of 300 patients (600 eyes) who had bilateral retinal detachment (RD) surgery between January 2005 and...
Driving with retinitis pigmentosa
4 December 2023
| Ian Reekie
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EYE - Vitreo-Retinal
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Inherited retinal disease, driving standards, retinal dystrophy, retinal imaging, retinitis pigmentosa, visual field testing
The authors present a study of 228 consecutive patients with a clinical or genetic diagnosis of retinitis pigmentosa. Data was collected prospectively between January 2012 and October 2022 in Perth, Australia. The study aimed to determine the proportion of patients...
Patient reported outcomes in adolescents with inherited retinal diseases
4 October 2023
| Ian Reekie
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EYE - Vitreo-Retinal
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PROM, Patient-reported outcomes, clinical trial, gene therapy, inherited retinal disease, pediatrics, retinal dystrophy
This was a two-centre validation study of two sets of patient reported outcome measures (PROMS) for adolescents (13-17- years-old) with inherited retinal diseases. The measures were the Michigan Retinal Degeneration Questionnaire (MRDQ) and the Michigan Vision-Related Anxiety Questionnaire (MVAQ). Both...
Rare presentation of giant cell arteritis in Chinese subjects
1 September 2023
| Claire Howard
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EYE - Neuro-ophthalmology
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non-arteritic anterior ischaemic optic neuropathy, Chinese, central retinal artery occlusion, Giant cell arteritis, ocular ischaemic syndrome, posterior ischaemic optic neuropathy
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...
Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity
3 April 2023
| Claire Howard
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EYE - Neuro-ophthalmology
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Ethambutol, coenzyme Q10, ethambutol toxic optic neuropathy, retinal ganglion cells, tuberculosis
Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...
A paradigm shift: re-defining success in retinal detachment repair
3 April 2023
| Zhihang Cheng
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EYE - Vitreo-Retinal
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Integrity, Outer retinal folds, Pneumatic retinopexy, Retinal detachment, Retinal displacement, Scleral buckle, Vitrectomy
The authors describe in this review article that functional outcomes vary with surgical technique for retinal detachment repair. Traditional definitions of surgical success have been shifted due to advances in imaging techniques. Assessment of the integrity of retinal reattachment including...
Does paediatric rhegmatogenous retinal detachment (RRD) obey Lincoff’s rule (LR)?
3 February 2023
| Su Young
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EYE - Vitreo-Retinal
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Lincoff‘s rule, pediatric, retinal break, rhegmatogenous retinal detachment
This was a retrospective study where 98 paediatric patients with RRD were identified through surgery records. Forty case sheets with complete record of ocular examination and surgical findings were analysed. Visible or suspected preoperative retinal break identified using the LR...
Treatment outcomes for retinal detachment
This is a retrospective, nationwide, multicentre study with retinal detachment (RD) in the Japan-RD registry between 2016 to 2017. The primary outcome was the estimated mean difference of postoperative corrected visual acuity (CVA) in six months and a propensity score...
Chorioretinal atrophy in punctate inner choroidopathy / multifocal choroiditis
1 December 2022
| Kelvin Cheng
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EYE - Vitreo-Retinal
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Chorioretinal atrophy, long-term outcome, multifocal choroiditis, punctate inner choroidopathy, white dots syndrome
This study reported the five-year outcomes of chorioretinal atrophy (CRA) progression in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) in 45 eyes of 36 patients. The mean age of the cohort of patients was 37 ±13.37 years...
Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Optic neuritis, axonal degeneration, neurofilament protein, retina, tissue
Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...
