Foveal displacement after macular hole surgery
5 April 2022
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Foveal displacement, internal limiting membrane peeling, metamorphopsia, papillofoveal distance, temporal inverted internal limiting membrane flap
Previous studies show that internal limiting membrane (ILM) peeling during macular hole surgery is associated with retinal shrinkage (microtubule depolymerization of the axons of the inner retina) and nasal shift of the fovea. A temporal inverted ILM flap technique was...
Detecting apoptosis in retinal cells
1 February 2022
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Apoptosis, Glaucoma, Imaging, Neurodegeneration, Retina
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
Occult central retinal artery occlusion
1 February 2022
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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CRAO, Central retinal artery occlusion, OCT, RAO, optical coherence tomography, retinal artery occlusion, spectral-domain optical coherence tomography
Central retinal artery occlusion (CRAO) is a sight-threatening condition resulting from occlusion of the central retinal artery and hypoperfusion of the inner retina. Early on, fundal examination may be normal. The authors present a retrospective case series of 11 patients...
Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
Incidence and outcomes of endophthalmitis with in-house compounded intravitreal bevacizumab injections
1 December 2021
| Su Young
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EYE - Vitreo-Retinal
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IVI, In-house compounded, bevacizumab, compounding pharmacy, endophthalmitis
This multicentre study examining a five-year period from 2014 to 2018 evaluated the incidence rate and outcomes of endophthalmitis after intravitreal injection of in-house compounded bevacizumab. In-house compounded syringes were prepared in compounding pharmacy using sterile standard operating guidelines. All...
OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema
1 December 2021
| Su Young
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EYE - Vitreo-Retinal
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Diabetic macular edema, aflibercept, optical coherence tomography, predictive, ranibizumab
This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....
Two-year interim safety results of the 0.2ug/day FAC intravitreal implant for the treatment of DMO
1 December 2021
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a 24-month interim prospective observational study of 95 previously steroid challenged patients (115 eyes) receiving intravitreal 0.2ug/day fluocinolone acetaid (FAC) implant for diabetic macular oedema (DMO) treatment. The mean IOP for pre- and post- FAC implants were stable,...
Retinal traction during ERM peeling
1 October 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Epiretinal membranes, Intraoperative Optical Coherence Tomography, Membrane peeling, Microperimetry
This prospective study aimed to quantify the retinal thickening induced by epiretinal membrane (ERM) peeling and to correlate this thickening with postoperative retinal function. Twenty-five patients who required surgery for idiopathic ERM were included in the study. The authors performed...
Retinal changes prior to hydroxychloroquine toxicity
1 October 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Ganglion cell layer, Hydroxychloroquine, Optical coherence tomography, Retina, Retinal thickness
In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...
Uveitis ocular toxoplasmosis
1 October 2021
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a retrospective study of 106 patients between March 2011 and June 2018, of 37 IgM +group and 69 IgM - group of patients. The clinical features, demographics of patients with ocular toxoplasmosis (OT) were studied according to the...
Visual outcomes after surgery for primary RRD in era of microincision vitrectomy
This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...
Sarcoid uveitis and its systemic associations
1 October 2021
| Tasmin Berman
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EYE - Vitreo-Retinal
This retrospective cross-sectional study examined systemic associations of sarcoid uveitis and association with uveitis clinical phenotype and ethnicity. Three hundred and sixty-two subjects with either definite or presumed sarcoid uveitis were identified and included in the study. Any subject with...
