You searched for "retinovascular"
The power of the full blood count
Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...Clinical relevance of the anatomic classification of neovascular age-related macular degeneration
The author explains why an OCT-based classification of neovascular AMD is needed and how these neovascular subtypes may help to predict patients’ long-term visual outcome. Age-related macular degeneration (AMD) is a chronic and progressive neurodegenerative process involving the macula in...
Two case reports of late onset adbucens nerve palsy following carotid-cavernous fistula treatment
1 December 2014
| Claire Howard
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EYE - Neuro-ophthalmology
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Abducens nerve palsy, carotid-cavernous fistula, transvenous embolisation
This report presents two cases of abducens palsy developing with late onset following endovascular treatment for carotid-cavernous fistula. Following this common and effective treatment for carotid-cavernous fistula, an immediate cranial nerve palsy is a common finding. It usually resolves spontaneously....
Treatment efficacy of stage 4 ROP
This study aimed to determine the efficacy of combined vitrectomy and anti-VEGF injection for advanced stage 4 ROP with extensive neovascular proliferation (NF). The study included nine infants; six bilateral and three unilateral. Seven were female and the mean gestational...
Aflibercept for the treatment of neovascular glaucoma
1 April 2016
| Anjali Gupta
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EYE - Glaucoma
The aim of this study was to investigate initial results regarding the treatment of neovascular glaucoma (NVG) with intravitreal aflibercept. NVG is classified into stages 0-3. In stages 1 and 2, abnormal vessel proliferation is seen with or without elevated...
Relationship between diabetic retinopathy and cerebrovascular reactivity changes
1 March 2024
| Claire Howard
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EYE - Neuro-ophthalmology
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Cerebral vasomotor reactivity, breath-holding index, diabetes mellitus, diabetic retinopathy, transcranial Doppler ultrasound
Cerebral micro-angiopathy caused by diabetes can manifest itself as an impairment in cerebrovascular reactivity. Transcranial doppler ultrasound (TCD) is a cost-effective and non-invasive way to measure the cerebrovascular reactivity. This study aimed to assess the relationship between the grade of...
What’s next in retinal imaging? Faster, deeper and full-on
Fast-evolving technological leaps are opening the way toward clinically useful ocular coherence angiography, generating 3-dimensional microvasculature maps without intravenous dye injection, as well as whole-eye imaging, handheld patient-operated optical coherence tomography (OCT) devices and, for challenging vitreoretinal procedures, integrated intraoperative...
Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
RPE tears after intravitreal Lucentis
1 February 2017
| Saruban Pasu
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EYE - Vitreo-Retinal
The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...
Is intracranial pressure affected by the valsalva manoeuvres and exercise?
31 May 2024
| Claire Howard
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EYE - Neuro-ophthalmology
Idiopathic intracranial hypertension (IIH) is characterised by elevated intracranial pressure (ICP), which leads to optic nerve head swelling and a risk of visual loss. The impact of straining and exercise on ICP regulation is poorly understood yet clinically relevant to...
Addressing medical risk factors for diabetes and understanding the new systemic treatments
1 February 2014
| Samantha S Mann
As global diabetes figures continue to rise, the importance of reducing the burden of macrovascular and microvascular complications of diabetes has never been so great. By 2025 it is estimated that five million people in the UK will have diabetes...
The risk factors associated with isolated microvascular third nerve palsy
3 April 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors used the Rochester Epidemiology Project for this retrospective case review of third nerve palsy. Inclusion criteria was adults >18 years, with new onset isolated microvascular third nerve palsy diagnosed within a 36-month period, with recovery or significant improvement,...
