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Influence of FLEx and SMILE on corneal nerve density and ocular surface
This was a prospective study designed to compare the influence of femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE) on the corneal nerve density and ocular surface for myopic correction. Thirty patients underwent bilateral lenticule extraction. One eye...Development of a modern surgical simulation suite to promote safer ophthalmic surgical training
For trainees, having access to surgical simulation equipment is more important than ever. The authors describe the creation of a bespoke teaching and training suite in Glasgow to help trainees develop their skills and promote surgical excellence. Simulation has become...Does a gut-eye axis exist?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does a gut-eye axis exist? Over a decade ago, the Human Microbiome Project was launched by...
Dead bag syndrome: a new and rare cause of late IOL dislocation
The dead bag syndrome has recently been described as a cause of late spontaneous intraocular lens (IOL) subluxation and / or dislocation. The capsular bag remains clear years after surgery and then becomes diaphanous and floppy. The authors explanted seven...
OCT in microtropia
The aim of this study was to assess whether OCT could be useful in detecting and documenting fixation in children with microtropia. The study used spectral domain OCT (Cirrus) in 15 patients (10 female, five male) and 10 control eyes....Jun/Jul 2014 Quiz
History An 80-year-old male had a cataract removed with intraocular lens (IOL) seven years previous. He presented with cloudy vision and it was noted that the IOL was intrinsically opaque. The IOL was replaced and sent for ophthalmic pathology assessment....How to diagnose and treat Acanthamoeba keratitis
Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...
Corneal thickness in patients with diabetic peripheral neuropathy
This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...Jun/Jul 2015 Quiz
History A 35-year-old male presents with bilateral corneal opacities. Examination shows a honeycomb-type dystrophy. A penetrating keratoplasty is performed and the specimen sent for ophthalmic histopathological assessment. Figure 1 is the haemotoxylin & eosin (H&E). Figure 2 is a Masson...
Autophagy in lens mitochondria loss
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
Corneal neurotisation with an allograft
This is the first reported use of an acellular nerve allograft for corneal neurotisation. Seven patients received a 7cm long commercially prepared acellular nerve allograft. This was coapted to a functioning supratrochlear, supraorbital or infraorbital nerve and then tunnelled to...
