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Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?

Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...

Meibomian gland dropout in patients with dry eyes

In this prospective study 264 patients with symptoms of dry eye were examined with a non-contact meibography system to assess the morphological changes in their meibomian glands. These patients were not previously diagnosed with meibomian gland dysfunction and patients with...

Clinical course of vitreomacular adhesion managed by initial observation

The purpose of this study was to investigate the clinical course of patients with idiopathic vitreomacular adhesion (VMA) with a noncomparative case series of patients who had clinical symptoms and spectral-domain optical coherence tomography findings consistent with VMA. The VMA...

Chronic drop use and trabeculectomy on tear osmolarity

Ocular surface disease (OSD) is common in patients chronically treated for glaucoma. This may be related to the drug itself but often to the preservatives in the medication. Much work has been done on the most common preservative, benzalkonium chloride...

Characteristics of Charles Bonnet syndrome in patients with neovascular AMD

This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...

Large series profiling skew deviation

A retrospective notes review was completed for patients identified as having skew deviation. The authors outline their exact definition of skew deviation within the methods of the paper. One hundred and fifty-seven patients were identified, it is not clear over...

Patients prefer vision from lasik than from smile in a contralateral-eye trial

This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...

Incidence of ocular myasthenia gravis and risk factors for conversion to generalised disease

This population based retrospective cohort study evaluates the incidence of ocular myasthenia gravis (OMG) as well as risk factors for transformation to generalised myasthenia gravis (GMG). Sixty-five patients (40 male and 25 female) with newly diagnosed with myasthenia gravis (MG)...

Presentation features of ocular neuromyotonia in children

The authors report five cases of ocular neuromyotonia (ON) in children following radiation treatment for brain tumours. Children were aged four, nine, twelve, five and nine years. Three had craniopharyngioma, one had fourth ventricle ependymoma and one had posterior fossa...

An atypical presentation of Vogt-Koyanagi-Harada Disease

The authors present a single case of atypical presentation of Vogt-Koyanagi-Harada disease. A 42-year-old female presented with unilateral visual loss associated with systemic symptoms of fever and headache. Initial ophthalmic examination revealed a unilateral neuroretinitis, however, investigations for infectious and...

PROMs in blepharoplasty

With the advent of clinical commissioning in NHS England the need to demonstrate the benefits of certain surgeries is becoming increasing common. Upper Lid blepharoplasty is a commonly performed operation and often seen as a cosmetic procedure. Danish visitation guidelines...

Treatment of severe chronic ocular graft-versus-host disease

A retrospective study from Cologne, Germany, between November 2012 to March 2015, of 17 patients with graft-versus-host disease (GVHD) treated with 100% single use vials autologous serum eye drops in sealed system. Visual acuity, corneal staining, frequency of artificial tears,...