You searched for "limbal"

141 results found

Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

MISS vs. conventional surgery

This was a prospective randomised parallel arm design study for 40 patients. Group 1 consisted of conventional strabismus surgery using the limbal approach and group 2 consisted of minimally invasive strabismus surgery (MISS). Mean age was 21.1±2.73 years for MISS...

Chemical injury

You are the on-call ophthalmologist. You receive a call from A&E regarding a 45-year-old man who sustained a chemical injury. He was mixing some cement, when a small amount entered his left eye. He was not wearing any protective goggles....

Van Herick Plus

This a consecutive cross-sectional study of 95 phakic patients over the age of 40-years-old. By applying a short, vertical slit beam, the inferior angle at the scleral-limbal junction at 6 o’clock position was evaluated, photographed and assessed by a ratio...

Diffuse lamellar keratitis

This study group reviewed cytokine- and chemokine-mediated mechanisms of diffuse lamellar keratitis (DLK) after lamellar corneal surgical procedures. DLK can occur early or late (months to decades) after all lamellar corneal surgeries, including laser in situ keratomileusis, small incision lenticule...

MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

Clinical outcomes of AMT in acute ocular chemical injury

This is a retrospective study of patients from two units in Germany and UK between 1998 and 2008. The ocular chemical burns were classified by Roper-Hall and Dua classifications. A total of 72 eyes of 54 patients aged 37.3 years...

Trabeculectomy ab interno (trabectome)

This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...

γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

Therapeutic ocular surface medium for persistent corneal epithelial defect

Corneal ulcers and persistent epithelial defects (PEDs) are caused by a variety of different insults to the cornea, which includes limbal epithelial stem cell failure. PED may be resistant to healing with standard therapy such as frequent ointments and /...

Erythropoietin in healing corneal epithelial defects in rabbits

Corneal epithelial defects heal slowly in patients with diabetes, limbal stem cell deficiency and severe chemical burns. Erythropoietin is a glycoprotein hormone that promotes red blood cell proliferation and inhibits apoptosis of erythroid progenitors as well as nonhematopoietic cells. In...

Conjunctival lesions in paediatric patients

This article documents the conjunctival lesions in paediatric patients from one unit from 2011–22 inclusive in the UK. There was a total of 85 cases with a mean age presentation of seven years old. Most common lesions were naevi (40%),...