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An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

5 April 2022 | | Ophthalmology, Cornea / External Eye Disease
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

Understanding amniotic membrane grafts

1 June 2019 | | Ophthalmology, Cornea / External Eye Disease
Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

Disseminated cutaneous zoster – a masquerade

1 February 2017 | | Cornea / External Eye Disease
Reactivation of varicella zoster infection in the elderly commonly presents to ophthalmologists as herpes zoster ophthalmicus (HZO), affecting the Va trigeminal dermatome. In patients with impaired immunity, zoster infection occurs with increased severity and may be complicated by visceral and...

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

3 April 2023 | | Ophthalmology
Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | Glaucoma, Genetics
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Meeting the needs of older patients in optics

1 February 2019 | | Cataract and Refractive, Optometry, Glaucoma, Retina / Uvea / Vitreous
Fiona Anderson discusses the important role of community-based eyecare practitioners in meeting the visual needs of ageing patients. It has been well documented that today we live for longer. Statistics show in 1997, around one in every six people (15.9%)...

Letter from America: Orbit and oculoplastic fellowship, University of California, San Diego

1 June 2014 | | Oculoplastics, Orbit
I was the fortunate recipient of the 2012 Keeler Scholarship, granting me the incredible opportunity to undertake a fellowship at the University of California, San Diego (UCSD) in orbital, oculoplastic and reconstructive surgery. My fellowship mentors were the renowned Professor...

The last three patients: dermatology (Patient Three)

3 August 2023 | | Dermatology
For the third and final reflection in this series (see Part 1 and Part 2), Professor Jonathan Rees recounts his experience of a patient with cancer who was failed by the NHS, and how their inadequate treatment illuminates some issues...

The clues of the eye – what is medical ophthalmology?

1 February 2022 |
The author looks at the increasingly significant role of medical ophthalmologists and the importance of integrative healthcare. The eye is a remarkable organ, and for decades we have been discovering intimations of pathology existing elsewhere in the body [1] simply...

Childhood glaucoma

1 February 2019 | | Glaucoma, Ophthalmology, Paediatric Ophthalmology / Strabismus
When a child is given a diagnosis of glaucoma, the impact upon that child and their family is enormous; equivalent to the diagnosis of a cancer [14]. This article outlines the knowledge, techniques and approaches that offer solutions to the...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

1 October 2014 | | Cornea / External Eye Disease
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Case series of toxic anterior segment syndrome

1 August 2019 | | Ophthalmology, Cataract and Refractive
Herein we report two cases of toxic anterior segment syndrome (TASS) following uneventful cataract surgery. Both patients presented 24 hours after their uneventful operations with painless blurred vision in the operated eye. The inflammatory reaction was controlled successfully with an...