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General population perceptions of severity of strabismus vs. angle of deviation and gender
The authors investigate whether the potential bias of gender, type of deviation, or size of deviation affected how strabismus was perceived among a general adult population. Eight photos were generated (head shots) of white people aged 25–30 years – purposive...Troubleshooting in LASIK
Contemporary laser in situ keratomileusis (LASIK) is safe and effective. It remains the dominant intervention in routine refractive surgery for a good reason: predictable results, rapid visual recovery, and relatively simple strategies for revision treatment. Over 95% of patients are...Globes in space: What would happen to our globes on the globe of Mars?
Many films have been made regarding life on alternative planets. With the Mars One mission approaching in 2023, there are high expectations regarding future interplanetary travel. The authors provide an ophthalmology perspective on what could happen to our eyes if...Resurfacing the ocular surface
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...Moorfields: Laser Course
Moorfields Education: Laser course for ophthalmic healthcare professionals
Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
Tacrolimus for endothelial rejection
This double-blinded randomised controlled trial tested the use of adjuvant topical Tacrolimus drops in cases of acute endothelial rejection in penetrating keratoplasty (PK). Patients with typical signs of endothelial rejection were randomised to receive either steroid therapy with topical Tacrolimus...
A randomised, controlled trial of oral propranolol in infantile haemangioma
Since its use was first reported in the New England Journal in 2008, propranolol has become the preferred treatment for infantile haemangiomas. However, there is no consensus as to the optimum dose or duration of treatment and there is a...
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema
Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...
Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome
A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...
Aspirin and upper lid surgery
This is a double-blind randomised controlled trial of preoperative aspirin versus placebo in patients undergoing upper lid blepharoplasty or ptosis surgery. All enrolled patients were already taking aspirin and no other anti-platelet or anticoagulant drugs. All patients either had no...
