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Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide

X-linked retinoschisis (XLRS) is an early onset hereditary retinal dystrophy. It is caused by mutations of the RS1 gene. Common manifestations of XLRS are schitic lesions at the macula, as well as infero-temporal schisis. Carbonic anhydrase inhibitors have previously been...

Reduced angle after BT for postop diplopia test

The authors undertook a retrospective study to evaluate the extent of reduced deviation after Botulinum toxin (BT) when used as a postoperative diplopia test. They evaluated effect in 39 patients: 32 exotropia and seven esotropia. The same BT dose was...

CVI features in an Indian population

This study describes the predisposing factors and ophthalmic characteristics of children with cortical visual impairment (CVI) at a tertiary centre in India. This was a retrospective cross-section study of children <16-years-old over a four-year period. A review of 88 patients...

Differences between ages and onset in functional network changes associated with reading Braille

Visual impairment affects learning ability, speed and accuracy required for reading, writing and learning memory in terms of educational performance. Braille training requires decoding of simple dots into meaningful words and sentences. The objectives of this study were to evaluate...

Impact of COVID-19 on orthoptic services during a recovery phase

The purpose of this study was to conduct a follow-up survey of orthoptic practice in the UK and Ireland during the summer 2020 interim recovery phase of the pandemic. This was a prospective cross-sectional survey from July 1 2020 to...

Visual snow syndrome: a review

Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...

General population perceptions of severity of strabismus vs. angle of deviation and gender

The authors investigate whether the potential bias of gender, type of deviation, or size of deviation affected how strabismus was perceived among a general adult population. Eight photos were generated (head shots) of white people aged 25–30 years – purposive...

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

Tacrolimus for endothelial rejection

This double-blinded randomised controlled trial tested the use of adjuvant topical Tacrolimus drops in cases of acute endothelial rejection in penetrating keratoplasty (PK). Patients with typical signs of endothelial rejection were randomised to receive either steroid therapy with topical Tacrolimus...

A randomised, controlled trial of oral propranolol in infantile haemangioma

Since its use was first reported in the New England Journal in 2008, propranolol has become the preferred treatment for infantile haemangiomas. However, there is no consensus as to the optimum dose or duration of treatment and there is a...

Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema

Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...