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In conversation with Robert F Walters, Orbis Trustee

Can you give us a brief overview of the organisation and its hope for the future? Orbis International is a global non-governmental organisation (NGO) which is dedicated to the prevention of blindness. We’ve now been going since 1982. We’re very...

Coming to terms with AI

A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...

Ovarian hormones drive onset of Sjogren’s disease in mice

Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...

Lacrimal gland carcinoma outcomes

This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...

IN FOCUS - The achievements and lasting effects of VISION 2020

Blindness is a major public health problem globally. The first estimate of global blindness by the World Health Organization (WHO) in 1972 provided a figure of 10 to 15 million, which was considered an underestimate [1]. In 1999, an extraordinary...

The results of the last survey Aug 2019

Thank you once again for participating in the survey. Some fascinating results once again. Almost one in five of us do not cancel cataract surgery on the day if the blood pressure (BP) is high, which I am surprised about....

New prognostic model for multiple sclerosis after optic neuritis presentation

The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...

What's trending Feb/Mar 2018

We are officially in 2018. New year, new you. The clock starts to turn to midnight and suddenly the excess and gluttony of the Christmas festive period comes to mind. “This year will be better”, we say to ourselves. The...

Ocular adnexal mantle cell lymphoma

In this study the authors compare primary ocular adnexal (OA) mantle cell lymphoma (MCL) with initially systemic MCL occurring over a 30-year period. MCL is a rare form of lymphoma accounting for 5-11% of OA lymphomas and therefore knowledge of...

Recurrent corneal erosions secondary to isotretinoin use

Isotretinoin (13–cis-retinoic acid) is the first line treatment for moderate to severe nodulocystic or papulopustular acne [1,2]. Although it is a safe medication, it has several adverse side-effects, including ophthalmic manifestations, as shown in Table 1 [3]. These side-effects need...

Avoiding pre-placed recti sutures in enucleation

This is a retrospective review of 40 patients who underwent enucleation using a non-conventional technique in which the recti muscles were detached from the sclera without pre-placing any sutures to secure the cut muscle ends. The surgery was only performed...

IN FOCUS - VISION 2020 LINKS Programme: the contribution of health partnerships to reduction in blindness worldwide

As other articles in this series (IN FOCUS Apr 2020) demonstrate, the year 2020 is highly significant in the eye care field. Naming a global initiative ‘VISION 2020: The Right to Sight’ in 1999 was a daring way to focus...