Journal Reviews

Importing iron to the retina

1 October 2017 | | Retina / Uvea / Vitreous | Age-related macular degeneration (AMD), Ceruloplasmi, Hepcidin, Hephaestin, Iron, Retina, Zip14, Zip8

In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...