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‘Pete’s Bogus Journey’ An autobiographical descent through a career in medicine now available.

There is no doubt that life is a bogus journey and it does not end well for any of us.

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...

Cystoid macular oedema following retinal detachment surgery

There are limited studies examining the incidence and risk factors for postoperative cystoid macular oedema (CMO) following rhegmatogenous retinal detachment (RRD) repair. Postoperative CMO is thought to be due to pro-inflammatory state, where numerous cytokines lead to tight junction dysfunction,...

Somatostatin protects retinal pericytes

Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...

Familial Mediterranean Fever and keratoconus

This retrospective case control study was conducted in the Genetic Diagnostic Centre in Turkey. It examined the prevalence of keratoconus in two groups; patients with Familial Mediterranean Fever (FMF) and age matched controls free of FMF, who were tested for...

Children’s visual acuity test without professional supervision

With increasing outpatient demand there has been an innovative shift to involve patients managing their own condition. This article compares visual testing carried out by an orthoptist with usual clinical methods, an orthoptist using the iSIGHT Test Pro and a...

Ranibizumab for the treatment of age-related macular degeneration

This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...

What's trending Oct/Nov 2022

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #teammates #warringtonwolves #keratoconus Robbie Mulhern, a professional rugby league player for Warrington Wolves, had never heard of keratoconus prior to...

Effect of one versus 24 hours diagnostic occlusion

The purpose of this study was to compare measurements taken after one and 24 hours of diagnostic occlusion in cases of basic and divergence excess types of intermittent exotropia. This was a prospective study of 43 patients (34 females) with...

Narrative review of idiopathic intracranial hypertension in children / adolescents

Idiopathic intracranial hypertension (IIH) affects both children and adults. Whilst the majority of IIH is mainly seen amongst adults, it also affects children. There are currently no clinical trials in IIH for those who are adolescents or children. The aims...

IN FOCUS - The achievements and lasting effects of VISION 2020

Blindness is a major public health problem globally. The first estimate of global blindness by the World Health Organization (WHO) in 1972 provided a figure of 10 to 15 million, which was considered an underestimate [1]. In 1999, an extraordinary...

Interview with Clinical Director of OpenEyes

Professor James Morgan is an Ophthalmic Consultant at Cardiff Hospital and also the clinical director of the OpenEyes programme. Given the national push for electronic records we felt hearing directly from James would be of interest. The interview was conducted...