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Impact of Eye Health Surveys and Partnerships in The Gambia

This article brings together the three national eye health surveys that have been undertaken in The Gambia between 1986 and 2019 and the impact that the results have had nationally and internationally. In it we describe the long-term capacity-strengthening for...

Working smarter not harder: How to transform eyecare delivery in the United Kingdom (part 1)

Are we doing enough to meet the current demands on ophthalmic services? In part one of a two-part series (see Part 2 here), Rosalind Harrison takes a look at how efficiency has been improved in eyecare services in the US....

Facilitators and barriers to conducting research

A survey of clinicians and researchers across the UK was conducted to identify barriers to research and potential solutions. The authors extracted details of studies listed on the UKCRN database that involved paediatric ophthalmology with recruitment of children. An e-survey...

Understanding amniotic membrane grafts

Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Changes in parafoveal retinal thickness after bariatric surgery in type 2 diabetics

Bariatric surgery induces an instant normalisation of blood glucose in as many as 80% of patients with type 2 diabetes. It has been previously reported that diabetic retinopathy (DR) is stable within one year after bariatric surgery. In this study,...

Corneal tattooing as treatment for bullous keratopathy

This retrospective study looked at differences in epithelial smoothing in patients with bullous keratopathy (BK) undergoing either corneal tattooing or anterior stromal puncture (ASP). Both procedures were carried out for symptomatic relief in eyes with poor visual potential. Chinese ink...

Cyclosporine A and pterygium fibroblasts

The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...

γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

Virtual ophthalmic conferences: learnings from the Covid-19 pandemic

The Covid-19 pandemic was the catalyst for a number of paradigm shifts in numerous industries. The demand for proxies that follow social distancing measures created a hotbed for digital solutions and transitioned these to social convention. In the aftermath, the...

If looks could kill – kohl and the eye

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: If looks could kill – kohl and the eye Human fascination with beautification can be traced...

Guide to Gaining Approval for a Clinical Study

This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...