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Journal Reviews

Retinal and Eye Research journal cover image.

Detecting glaucoma with only OCT

3 April 2023 | Zhihang Cheng | EYE - Glaucoma | Glaucoma, OCT, Optical coherence tomography, Retinal ganglion cell layer, Retinal nerve fiber layer

In this review article, the authors describe a probability model based upon only OCT to detect glaucoma. They explain how normal anatomical variation can lead to false positives and applying a model to account for this improves specificity. The application...

Occult central retinal artery occlusion

1 February 2022 | Kurt Spiteri Cornish | EYE - Vitreo-Retinal | CRAO, Central retinal artery occlusion, OCT, RAO, optical coherence tomography, retinal artery occlusion, spectral-domain optical coherence tomography

Central retinal artery occlusion (CRAO) is a sight-threatening condition resulting from occlusion of the central retinal artery and hypoperfusion of the inner retina. Early on, fundal examination may be normal. The authors present a retrospective case series of 11 patients...

Ophthalmologica journal cover image

Sickle cell maculopathy

1 October 2021 | Sofia Rokerya | EYE - Vitreo-Retinal | OCT imaging, Sickle cell disease, Sickle cell maculopathy, Visual impairment

This paper reports the result of a prospective study to analyse the prevalence of sickle cell maculopathy (SCM) and its associations with age, sex, genotype, proliferative sickle cell retinopathy (PSR) stage, and the impact on visual acuity (VA). This study...

Transient macular thinning with Densiron 68

4 August 2021 | Kurt Spiteri Cornish | EYE - Vitreo-Retinal | OCT, Retinal detachment, heavy silicone oil, macula

Densiron 68 is a heavy silicone oil (HSO) used to treat rhegmatogenous retinal detachments (RRD) with inferior retinal breaks. The authors compared changes in retinal thickness during and after the use of Densiron endotamponade, and looked at any association between...

Investigating the effect of signal strength on mean retinal nerve fibre layer

7 December 2020 | Claire Howard | EYE - Neuro-ophthalmology | OCT, RNFL, Retinal nerve fiber layer, Spectralis, optical coherence tomography, signal strength

The aim of this study was to determine the effect of signal strength on mean retinal nerve fibre layer (RNFL) using spectralis optical coherence tomography (S-OCT). Thirty normal subjects were imaged with S-OCT using variably dense Bangerter foils to alter...

Glaucoma and capillary perfusion

1 August 2019 | Kurt Spiteri Cornish | EYE - Glaucoma | Glaucoma, OCTA, field of vision, intraocular pressure, macula, optic nerve

Elevated IOP is important but not the sole factor responsible for retinal ganglion cell (RGC) death and optic nerve damage in glaucoma. There is increasing evidence that visual loss correlates with macular inner retinal thinning. A total of 148 eyes...

OCT changes in chronic optic neuropathy

1 October 2017 | Claire Howard | EYE - Neuro-ophthalmology | OCT angiography, optic neuropathy, peripapillary capillaries

The authors evaluated optical coherence tomography (OCT) angiography in 10 patients who suffered various types of chronic optic neuropathies. Glaucoma is known to cause a decrease in peripapillary perfused capillary density on OCT angiography. However, other optic neuropathies have not...

Long-term retinal changes following unilateral retrobulbar optic neuritis

1 June 2015 | Claire Howard | EYE - Neuro-ophthalmology | OCT, optic neuritis, optical coherence tomography, RNFL, steroid

The aim of this study was to assess the longitudinal changes in retinal nerve fibre layer (RNFL) thickness after a first attack of optic neuritis and to investigate the impact of treatment on RNFL thinning at one year after the...

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