You searched for "AMD"

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Possible COVID-19 related maculopathy

COVID-19 is being investigated as a potential cause for various ocular diseases, with growing evidence of related retinal vascular changes, that vary from isolated cotton wool spots and retinal haemorrhages to retinal vascular occlusions [1.2]. COVID-related macular affection has also...

Quality matters in the management of serious eye disorders

The author discusses the first quality standard for serious eye disorders from NICE and takes a look at new care models for enhanced service delivery. Patient backlogs pose risks to patient safety, with research showing that people are losing sight...

Visual retraining for homonymous hemianopia following stroke

This is a clinical trial evaluating the efficacy of motion discrimination training as a potential therapy for stroke-induced hemianopic visual field defects involving 48 patients. They were randomised into two arms, one intervention (deficit-field) and one control (sighted-field). Patients were...

Broadening of treatment options for potentially blinding retinal conditions

Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...

Meta-analysis of treating meibomian gland dysfunction (MGD) with topical / oral azithromycin

This study pooled the clinical outcomes of 18 high-quality studies managing MGD with azithromycin. Symptom score was the primary and clinical signs were the secondary outcome measures. Overall effectiveness of topical azithromycin (TA) and oral azithromycin (OA) was measured by...

AI breakthrough brings geographic atrophy treatment a step closer

A team led by Dr Konstantinos Balaskas at Moorfields Eye Hospital Reading Centre has developed a fully automated, deep-learning model (algorithm) that can detect and quantify geographic atrophy using standard optical coherence tomography (OCT) scans.

Macular pigment and dark adaptation in older population with normal maculas

Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...

Phakic iris clip lenses and endothelial cell loss

This retrospective observational study included long-term results on endothelial cell losses in highly myopic eyes, which underwent phakic iris-clip lens implantations. Included in the analysis were 113 eyes with mean preoperative spherical equivalent (SEQ) of -14.67 +/- 5.15 Diopters (D)....

What is paracentral acute middle maculopathy?

This is a review article characterising a clinical entity called paracentral acute middle maculopathy (PAMM). The article highlights the fact that retinal capillary plexuses are organised predominantly into three trilaminar capillary layers occupying the area between the nerve fibre layer...

What's trending Jun/Jul 2018

#BusyPhillips #photokeratitis #sunglasses Last time, we were in the throes of the Beast from the East. Here in the UK, it’s been a long winter and cold start to spring. The days are longer now, thanks to British Summer Time,...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...