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ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

Effect of the COVID-19 Urgent Eyecare Service on patient referrals to general practitioners and Hospital Eye Service

The COVID-19 Urgent Eyecare Services (CUES) was developed to relieve the demands of hospital ophthalmology, aiming to allow patients to have remote consultations and be managed by community optometric practice. This was because access to Hospital Eye Service (HES) Ophthalmic...

The role of spectral-domain OCT RNFL in revealing a pituitary adenoma with atypical visual fields

Pituitary adenomas classically cause bitemporal hemianopia by compressing the optic chiasm. However, in some cases, the pattern of visual field loss may be atypical and mimic homonymous hemianopia, depending on the direction and extent of tumour expansion. Spectral-domain optical coherence...

Iris chafing from displaced single-piece acrylic IOL

A 74-year-old man had persistent 3+ cell one month following left eye cataract extraction, complicated by anterior capsular rent and zonular dialysis at 7 o’clock, with single-piece acrylic intraocular lens implantation (IOL) in the capsular bag. Figure 1: Haptic-like transillumination...

My Top Five: Emerging robotic and automated innovations in ophthalmological surgery

Robotic technology is redefining the landscape of ophthalmological surgery by enabling micron-level precision and control beyond human capability. Intraocular microsurgery remains challenging to perform, with concerns about accuracy, tremor, precision, depth perception and dexterity. Moreover, conventional surgical tools have only...

The miracle of multi-professional working in modern-day eyecare

"It’s a Tuesday morning, and I’m in the presence of one of the most mind-boggling accomplishments in human history. This thing is so astounding in its complexity and scope, it makes the Panama Canal look like a third grader’s craft...

Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?

Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...

My Top Five: Key insights from recent research into uveitis in adults

Uveitis, characterised by inflammation of the uvea – the eye’s middle layer comprising the iris, ciliary body, and choroid – remains a leading cause of visual impairment worldwide [1]. It primarily affects adults aged 20–50 years. Untreated uveitis may cause...

Patient care a family affair at Newcastle-Under-Lyme eye hospital

With Mother’s Day just around the corner, mother and daughter Lisa Moors and Hannah Young won’t have to wait until next Sunday to spend time together - the pair work side-by-side, caring for hundreds of cataract surgery patients each week...

‘Step Up For Nystagmus’ this Nystagmus Awareness Day

Monday 20 June, the Nystagmus Network marks Nystagmus Awareness Day by asking supporters to ‘Step Up For Nystagmus’ to raise awareness of this complex visual impairment.

Risks factors for graft preparation failure in DMEK

Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...

Acanthamoeba ability to adhere to different contact lenses

This study tested ability of Acanthamoeba lugdunensis trophozoites to adhere to silicon hydrogel contact lenses (SHCL) and how this is influenced by different multipurpose contact lens solutions (MPS). Three generations of SHCL were tested: first generation – Air Optix, second...