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263 results found

Ovarian hormones drive onset of Sjogren’s disease in mice

Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...

Good News from Switzerland: A History of Retinal Reattachment Surgery

In one concise volume the reader learns of the recent rapid evolution in vitreoretinal (VR) surgery. The pioneering innovators were often remarkable personalities and this book helps to bring them to life. Prior to 1929 victims of retinal detachment were...

Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

Incidence and risk factors of late in the bag intraocular lens dislocation

The aim of this study was to identify risk factors for late in the bag dislocation over a 21 year period. Worldwide the incidence varies from 0.05% to 3.0%. In this Swedish study they report an increase in incidence in...

Intravitreal injection related endophthalmitis

This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...

Conservative surgical management of optic disc pit maculopathy

Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...

Are corneal guttata an additional risk factor in complicated cataract surgery needing a future corneal transplant?

This registry-based cohort study from Sweden utilised data from the Swedish National Cataract Registry and the Swedish Cornea Transplant Registry. Patients who underwent phacoemulsification with a posterior intraocular lens between 2010 and 2012 numbered 192,476. Of these cases, 288 underwent...

Transient macular thinning with Densiron 68

Densiron 68 is a heavy silicone oil (HSO) used to treat rhegmatogenous retinal detachments (RRD) with inferior retinal breaks. The authors compared changes in retinal thickness during and after the use of Densiron endotamponade, and looked at any association between...

Trabeculectomy with MMC in post-traumatic angle recession glaucoma

This study aimed to evaluate the outcomes of primary trabeculectomy with mitomycin-C (trab MMC) in phakic eyes with post-traumatic angle recession glaucoma with no prior intraocular surgery. Thirty-two phakic eyes of 32 patients who underwent trab MMC between January-2002 and...

Characteristics of bilateral retinal detachment

This was a retrospective study based at a tertiary centre which analysed the specific characteristics of bilateral Rhegmatogeous detachment, taken from the review notes of 300 patients (600 eyes) who had bilateral retinal detachment (RD) surgery between January 2005 and...

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Update: Non-infectious retinal vasculitis

This review article summarises the update on non-infectious retinal vasculitis (RV). It is primarily classified based on the type of retinal vessels involved and further sub-classified as occlusive or nonocclusive. Clinically it can occur as an isolated ocular entity or...