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Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...Vitreomacular traction: natural course vs. vitrectomy vs. ocriplasmin
Over time, the vitreous gel completely separates from the retina in a process known as a posterior vitreous detachment (PVD). In some instances, however, the vitreous does not detach entirely and remains adherent to the macula. The term vitreomacular traction...
Simple approach to prevent capsule tear-out during capsulorhexis creation in hyper mature cataracts
Puncturing the anterior capsule in the anterior chamber so that the pressure falls below intracapsular tension causes the rhexis to extend out to the equator. If this develops into a tear that wraps around the entire lens it is called...Patient safety – is this achieved in optometry with CET?
Collecting points and ticking boxes – as we come to the end of another three year cycle of continuing education and training (CET), the rush to ensure that everything has been completed on the myGOC (General Optical Council) dashboard feels...Vision on the line: Managing orbital trauma in a 30-year-old surgeon after a football injury
Blunt orbital trauma is a common consequence of sports injuries. Although retrobulbar haemorrhage is frequently associated with orbital compartment syndrome (OCS), the severity of clinical signs can outweigh imaging findings. Early recognition and intervention, such as lateral canthotomy and cantholysis...CALL TO ACTION: Ophthalmology on Myanmar / Thailand border: do you have any redundant kit?
In 1990, the late Doctor Frank Green, a consultant ophthalmologist in Aberdeen, along with Doctor Phillip Ambler, a GP with ophthalmic training, responded to an invitation to provide ophthalmic care for Karen refugees on the northern and eastern Myanmar borders....Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...Are hospital cataract services managing more complex cases?
An audit of referral pathways and case mix in hospital cataract services. Cataract is the leading cause of irreversible blindness worldwide, causing severe visual impairment, particularly within ageing populations [1]. Gradual lens opacification impairs contrast sensitivity, visual acuity and overall...Lord Trees and Baroness Sugg call to end Neglected Tropical Diseases with charity coalition at Westminster event
UK Coalition against Neglected Tropical Diseases works alongside co-host parliamentary reception in the House of Lords.Effect of minor trauma in eyes with previously undiagnosed angioid streaks
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...Are social media promoting ocular protection in the community?
During the Covid-19 pandemic, many countries worldwide introduced lockdown measures to control infection, causing people to spend more time at home. This resulted in reports of increasing incidences of do-it-yourself (DIY)-related trauma. When the Covid-19 pandemic started in December 2019,...
