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Features of AMD treatment non-responders

This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...

Risk of developing pseudotumor cerebri in women using a levonorgesteral intrauterine device

Pseudotumor cerebri (PCT) is a disorder causing increased intracranial pressure without a mass lesion, usually seen in obese women of childbearing age. Idiopathic intracranial hypertension is an idiopathic form of the disorder, but several medications have been associated with the...

Orbital rhabdomyosarcoma treatment characteristics

The aim of this study was to review the clinical presentation, management, local and systemic outcomes of 14 orbital rhabdomyosarcoma (OR) cases with the focus on the role of surgery as treatment. The mean age at presentation was eight years...

Systematic review on vergence neural pathways

A full systematic review of the literature was carried out by the authors, to identify literature available on vergence neural pathways and associated disorders. The review included articles related to vergence neural pathways, along with articles that discussed the anatomy,...

A novel presentation of optic disc oedema with syphilis

Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....

Use of group consultations in the management of idiopathic intracranial hypertension

The incidence of idiopathic intracranial hypertension (IIH) has risen by >100% between 2002 and 2016 in the UK, in association with rising obesity rates. This increasing incidence has inevitably led to increased pressures on service capacity. Evidence for other conditions...

Using lumbar puncture as a diagnostic tool of IIH when the presentation is typical

The authors present the findings of a retrospective observational chart review across three neuro-ophthalmology clinics. Databases at each clinic were searched using inclusion criteria based on established diagnostic criteria for idiopathic intracranial hypertension (IIH). Cases with missing data, atypical findings...

Natural history of idiopathic intracranial hypertension depending on incidental or symptomatic presentation

The authors present a large retrospective review cohort of consecutive patients diagnosed or presumed idiopathic intracranial hypertension (IIH) over a three-year period at a single tertiary centre. Patients on medication with a known aetiology for IIH were excluded. The cohort...

Features of childhood cases of sixth nerve palsy

Based on limited information available for cranial nerve palsies in children, the authors aimed to collect data on new onset paediatric sixth nerve palsies in a UK population. This was a retrospective study over 10 years for children aged <18...

Should we be looking for anemia in the presence of papilloedema?

The authors present a retrospective case notes review of patients diagnosed with idiopathic intracranial hypertension (IIH) presenting to a tertiary neuro-ophthalmology clinic over a 32-month period. The IIH group were age and sex matched with other patients attending the clinic...