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Triamcinolone (TA) deposits following subcutaneous injection to treat chalazion

Chalazia are chronic lipogranulomatous inflammations of the eyelid secondary to a blocked meibomian gland. Whilst most resolve spontaneously, certain chalazia warrant treatment. Options include incision and curettage (I&C), lesion excision, intralesional steroid injections, and botox injections [1]. I&C is usually...

The results of the last survey Jun25

The first question refers to whether we check blood glucose levels prior to cataract surgery. Almost three quarters of you do which was interesting. We know that poor glycaemic control (manifesting as a raised HbA1c) has implications for wound healing...

Efficacy of BT as a treatment for cranial nerve palsy in acute and chronic cases

The authors performed a meta-analysis of all patients’ treatment with botulinum toxin (BT) for cranial nerve palsy (CNP) to determine the efficacy of BT in the treatment of CNP due to a variety of causes. The search identified 1129 articles...

How many injections in nAMD: ranibizumab vs. aflibercept

Intravitreal anti-VEGF injections make up a large proportion of the workload in ophthalmology clinics. Since the introduction of aflibercept with eight weekly injections there has been an option to use a treatment which may require less treatment, with potential cost...

Effect of single intravitreal injection of bevacizumab on contrast sensitivity in patients with central retinal vein occlusion

Central retinal vein occlusion is the second most common retinal vascular disorder after diabetic retinopathy. There are many studies reporting the efficacy of intravitreal anti-VEGF injections for macular oedema secondary to retinal vein occlusions. This paper looks at the contrast...

RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...

Ozurdex use in noninfectious uveitis

Burkholder et al. reported the practice patterns of 45 respondents of approximately 176 surveyed members of the American Uveitis Society regarding the use of the Ozurdex implant. Most respondents performed the injection in either a procedure (41.0%) or clinic (23.1%)...

Efficacy of intravitreal dexamethasone implant in patients with persistent macular oedema

Chronic cystoid macular oedema (CME) can develop secondary to various pathologies such as diabetic maculopathy, retinal vein occlusion and uveitis. It can cause significant visual impairment and macular damage. The therapeutic effect of corticosteroids in CME is through one or...

Evisceration in India: demographic and clinical trends from a large multicentre cohort study

In this multicentre cohort study, the authors investigated a total of 2071 patients who underwent evisceration with primary implant placement over a six-year period at four tertiary eyecare centres in India. Out of 1,345,480 new ophthalmic presentations during the study...

Cytomegalovirus retinitis post intravitreal triamcinolone in an immunocompetent patient with juvenile glaucoma

Figure 1: Fundus photograph shows active CMV retinitis four weeks after IVTA in the right eye. Figure 2: Fundus photograph of the left eye with no CMV retinitis; atrophic disc as a result of juvenile glaucoma. Case report A 29-year-old...

Does intravitreal bevacizumab help in diabetic retinopathy related vitreous haemorrhage?

This retrospective, interventional case series, aimed to assess the effectiveness of intravitreal bevacizumab (IVB) in vitreous haemorrhage secondary to proliferative diabetic retinopathy. The primary outcome was the rate of vitrectomy (PPV) after IVB, with secondary outcomes the number of IVB...

What's trending Oct/Nov 2020

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #oldEnglish #herbalremedies Researchers from the University of Warwick, investigating natural remedies to treat bacterial infections, have discovered a potential new treatment....