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Long-term outcomes of using intraoperative relaxed muscle positioning technique in thyroid eye disease

The authors present a retrospective case review of consecutive patients undergoing ocular muscle surgery by one ophthalmologist using the intraoperative relaxed muscle positioning (IRMP) technique for thyroid eye disease (TED)-associated strabismus over a 23-year period. The following data were extracted...

Twenty-four hour IOP patterns in patients with thyroid eye disease (OO/GL)

Elevated IOP in patients with thyroid eye disease (TED) can be caused by restriction and compression of the globe by enlarged extraocular muscles, elevated episcleral venous pressure and increased mucopolysaccharide deposition in the trabecular meshwork. Although previous studies have investigated...

Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease

In recent years artificial tear drops addressing tear film osmolarity have come onto the market. Increased tear evaporation and reduced tear volume results in tear hyperosmolarity. This triggers an inflammatory process leading to apoptosis of goblet and epithelial cells. Trehalose,...

Neuro-ophthalmic disease patterns in Southeast Asia with particular reference to giant cell arteritis

As indicated in an earlier article in Eye News [1] Dr Cullen was invited in 2000 to the Singapore National Eye Centre (SNEC) as visiting Professor with a specific remit to set up a specialist neuro-ophthalmology service, which was the...

Progress in retinal disease management: Highlights of the Retina Day, RCOphth 2025 Annual Congress

The Retina Day meeting at the Royal College of Ophthalmologists (RCOphth) 2025 Annual Congress in Liverpool was held on 22 May 2025. This report highlights 10 selected topics of interest to subspecialists and general ophthalmologists. Decarbonising anti-VEGF clinics (or making...

Changes in ocular biomarkers in Vogt-Koyanagi-Harada disease after pulse steroid therapy

This retrospective study aimed to evaluate the early and chronological changes in ocular biomarkers in patients of Vogt Koyanagi Harada (VKH) disease who received pulse steroid therapy. It further aimed to identify which biomarkers correlated with the best corrected visual...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics

The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...

Medical and eye health teams defy odds to deliver treatments for trachoma in Ethiopia, but millions worldwide risk return of disease amid UK aid cuts

Ophthalmologists, nurses, and eye health workers in Ethiopia defied the odds to treat millions with trachoma-fighting antibiotics and surgeries - despite cuts to UK Aid assistance threatening eye care. This World Neglected Tropical Diseases Day Orbis, the international eye care...

Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges

Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...

Can OCT predict Alzheimer’s disease?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Can OCT predict Alzheimer’s disease? In 1986 Hinton et al. demonstrated evidence of optic nerve degeneration...

Diagnoses of dry eye disease double within a year

Over a third of Britons haven’t had an eye test within the last two years, while one in five have not had an eye test due to financial struggles.