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The use of adalimumab for relapse in patients with Vogt-Koyanagi-Harada disease
In this retrospective, multi-centre, cohort study, the efficacy and safety of Adalimumab (ADA) treatment for the exacerbation or recurrence of Vogt-Koyanagi-Harada (VKH) patients was assessed by investigating the medical records of patients who had received ADA treatment for more than...Eye disease patients have more opportunity than ever to take part in NHS research studies
A new report highlights how 76% of UK hospitals now offer patients the opportunity to take part in studies of eye disease to improve research and innovation. ‘Ophthalmology research in the UK’s National Health Service: the structure and performance of...An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease
Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....
Twenty-four hour IOP patterns in patients with thyroid eye disease (OO/GL)
Elevated IOP in patients with thyroid eye disease (TED) can be caused by restriction and compression of the globe by enlarged extraocular muscles, elevated episcleral venous pressure and increased mucopolysaccharide deposition in the trabecular meshwork. Although previous studies have investigated...
Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease
In recent years artificial tear drops addressing tear film osmolarity have come onto the market. Increased tear evaporation and reduced tear volume results in tear hyperosmolarity. This triggers an inflammatory process leading to apoptosis of goblet and epithelial cells. Trehalose,...
Long-term outcomes of using intraoperative relaxed muscle positioning technique in thyroid eye disease
The authors present a retrospective case review of consecutive patients undergoing ocular muscle surgery by one ophthalmologist using the intraoperative relaxed muscle positioning (IRMP) technique for thyroid eye disease (TED)-associated strabismus over a 23-year period. The following data were extracted...Neuro-ophthalmic disease patterns in Southeast Asia with particular reference to giant cell arteritis
As indicated in an earlier article in Eye News [1] Dr Cullen was invited in 2000 to the Singapore National Eye Centre (SNEC) as visiting Professor with a specific remit to set up a specialist neuro-ophthalmology service, which was the...Progress in retinal disease management: Highlights of the Retina Day, RCOphth 2025 Annual Congress
The Retina Day meeting at the Royal College of Ophthalmologists (RCOphth) 2025 Annual Congress in Liverpool was held on 22 May 2025. This report highlights 10 selected topics of interest to subspecialists and general ophthalmologists. Decarbonising anti-VEGF clinics (or making...Personalising the management of dry eye disease: TFOS DEWS III updates evidence-based recommendations
Dry eye disease (DED) is a heterogenous condition that arises from various aetiologic factors and leads to tear film instability, ocular surface damage and neurosensory changes. Symptoms of DED include ocular dryness, burning, itching, pain and visual impairment. An evidence-based...
