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609 results found

Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus

This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...

Hering’s response in ptosis surgery

his is a prospective study of the Hering’s response in patients undergoing Muller’s muscle-conjunctival resection (MMCR) ptosis surgery, with a particular reference to the accuracy of preoperative phenylephrine testing. Patients with unilateral ptosis were assessed clinically preoperatively, in the immediate...

Improved efficacy expected with second-generation microinvasive glaucoma surgery (MIGS) devices

Microinvasive surgical approaches to primary open-angle glaucoma (POAG) offer minimally traumatic options for effective intraocular pressure (IOP) reduction in appropriately selected glaucoma patients. Increases in laser trabeculoplasty rates and wider adoption of glaucoma drainage device filtration procedures, together with the...

Recurrent unilateral preseptal cellulitis secondary to herpes simplex virus infection

Introduction Periorbital (sometimes called preseptal cellulitis) is a common condition which on its own is not normally an ophthalmic or surgical emergency, however it has the potential to cause severe and serious morbidity in cases where the infection has crossed...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Dilate or not in subconjunctival haemorrhage?

There is often surprisingly little evidence in common clinical conditions. Spontaneous non-traumatic subconjunctival haemorrhage (SCH) is frequently encountered in emergency and walk-in clinic visits. In some centres, a dilated fundus exam is performed to exclude retinal pathology. This retrospective study...

Ophthalmology history and examination – a guide for medical students

*First author Students have very little exposure to ophthalmology during their years at medical school. Teaching consists of a handful of lectures followed by a short placement in which students are expected to practise histories and examinations on patients with...

Limbal melanocytes and the stem cell niche

The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...

Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery

Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...

Combined Vismodegib and Mohs surgery

This is a report of eight patients with locally advanced periocular basal cell carcinoma who were treated with Vismodegib prior to Mohs micrographic surgery. The rationale for the combined treatment plan was that long-term Vismodegib is poorly tolerated due to...

OSCAR for anterior approach ptosis surgery

The authors report an International Council of Ophthalmology (ICO) Ophthalmology Surgical Competency Assessment Rubric (OSCAR) for anterior approach ptosis surgery. An international panel of content experts, representing Australia, India, Iran, Italy, Turkey, United Kingdom and the United States of America...

Ocular adnexal marginal zone b-cell lymphoma

This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...