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Recurrent corneal erosions secondary to isotretinoin use

Isotretinoin (13–cis-retinoic acid) is the first line treatment for moderate to severe nodulocystic or papulopustular acne [1,2]. Although it is a safe medication, it has several adverse side-effects, including ophthalmic manifestations, as shown in Table 1 [3]. These side-effects need...

Demodex blepharitis: A transatlantic comparison of treatments available in the UK and US

Demodex blepharitis is widely recognised among eyecare professionals as an important cause of chronic lid margin inflammation, dry eye and ocular surface diseases. The characteristic feature for diagnosis is the presence of waxy deposit at the lash bases on slit...

The role of inflammation in the pathophysiology of DMO

Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Corectopia grading

The authors present a novel corectopia classification system using 28 eyes of 28 patients with or without corectopia. The grading and classification system for corectopia was as follows: (i) Direction of decentration: superior (DecS), superonasal (DecSN), nasal (DecN), inferonasal (DecIN),...

Effective treatment for rare sight-threatening infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

New survey reveals over half of UK adults expect to experience sight loss in the next 10 years.

This survey and media article are fully organised and funded by Apellis. New survey reveals over half of UK adults expect to experience sight loss in the next 10 years. Yet more than one in four (29%) of those surveyed...

Conference Report: RCOphth 2025

This year’s Royal College of Ophthalmologists Annual Congress in Liverpool brought together eyecare professionals from across the country and beyond for four days of thought-provoking content, collaborative discussion and exciting glimpses into the future of ophthalmology. The opening day was...

Identifying drugs associated with intraoperative floppy iris syndrome

Before David Chang MD from the University of California found out about intraoperative floppy iris syndrome (IFIS), ophthalmologists were mystified each time they came across cataract surgeries that were characterised by sudden intraoperative iris prolapse and pupil constriction. The biggest...

The art of ophthalmic simulations

For Dec/Jan 2024, I got in touch with Nicky Webster, a Principal 3D Artist at FundamentalVR (https://fundamentalsurgery.com). Nicky is also a registered medical illustrator, healthcare scientist and medical photographer. With over 18 years of experience working in various disciplines within...

What can artificial intelligence do to improve sustainability in the delivery of ophthalmic care?

The 2025 NHS 10-year plan, titled ‘Fit for the Future’, emphasises a significant shift from analogue to digital, with a strong focus on integrating AI and other technologies to transform healthcare. The plan aims to make the NHS the "most...

Reducing myopia progression

This paper reports a literature review to discuss the environmental considerations and treatment options that can prevent the progression of myopia, including time spent outdoors, reduction of near vision activities, spectacle types, contact lens type and pharmacological treatment. The review...

Another plant-based remedy for the eye?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Another plant-based remedy for the eye? What do the nicknames Mary Jane, tea, and 420 all...