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Acute retinal necrosis presumably caused by Epstein-Barr virus infection

1 October 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Acute retinal necrosis (ARN) is an uncommon, but serious and potentially blinding condition. ARN is characterised by panuveitis, occlusive vasculopathy and progressive peripheral necrotising retinitis. The diagnosis is clinical but confirmation is sought via aqueous and vitreous sampling. Varicella zoster...
Cornea journal cover image.

Boston type I keratoprosthesis for limbal stem cell deficiency

1 October 2016 | | EYE - Cornea, EYE - General
Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...
Ophthalmologica journal front cover image.

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

1 October 2019 | | EYE - Vitreo-Retinal
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
Pediatric Ophthalmology & Strabismus journal cover

Association of sleep problems in children with visual impairment

1 December 2022 | | EYE - Paediatrics, EYE - Strabismus
The intention of this study was to investigate sleep problems in children who had a wide range of visual impairments. Recruitment was via an online survey distributed through the National Federation of Blind and National Organisation for Albinism and Hypopigmentation,...

Thyroid eye disease

22 September 2021 | | EYE - Orbit, EYE - General
Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....

How to examine the visual system Part 2: Accommodation, pupils, fundoscopy and additional tests

1 August 2014 | | EYE - Vitreo-Retinal
Examining the visual system can be a tricky skill for medical students to master, yet it is a task that is frequently tested in examinations. This is the second of a two-part series of articles, which together aim to improve...

What not to miss in neuro-ophthalmology Part 1

1 April 2018 | EYE - Neuro-ophthalmology
Neuro-ophthalmology is a complex and difficult subspecialty in ophthalmology. It has several connections to neurology, neuro-surgery, rheumatology as well as many other medical specialties. Working in an multidisciplinary team (MDT) environment is key to success in this subspecialty as mistakes...

What not to miss in neuro-ophthalmology Part 2

1 August 2018 | EYE - Neuro-ophthalmology
As mentioned previously there are several conditions in neuro-ophthalmology that should not be missed by the general ophthalmologist as well as ophthalmology trainees. We discussed in the first part some of these conditions including third cranial nerve palsies, giant cell...

Papilloedema: an update

1 June 2016 | | EYE - Neuro-ophthalmology
Some readers may have seen a recent report in the national newspapers of the case of a teenage girl with persistent severe headache associated with a fatal brain tumour having been undiagnosed despite many consultations with her medical advisers. It...

My neuro-ophthalmology elective: Weill Cornell Medicine

3 June 2026 | | EYE - Neuro-ophthalmology
First and foremost, it’s important to evaluate the reasons for pursuing a clinical elective in the US. Personally, I had been set on completing my specialty training (residency) in the US since my third year of medical school, and an...

Toxoplasmosis and the associated retinochoroiditis: important facts and when to treat

1 April 2017 | | EYE - Vitreo-Retinal
Annie SeeWah Tung provides an overview of toxoplasmosis retinochoroiditis, including guidance on which cases should be treated and the treatment options. Toxoplasmosis retinochoroiditis is an infectious condition that is characterised by retinochoroidal lesions commonly in the posterior pole and is...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

3 April 2023 |
Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...