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Optical coherence tomography – reinventing the eye examination

1 October 2016 | | EYE - Vitreo-Retinal, EYE - Imaging
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...

Genetic profiling for personalised healthcare solutions in AMD – an update

1 August 2015 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...
Clinical and Experimental Ophthalmology journal cover image

Microdroplet and splatter contamination during phacoemulsification in COVID-19 era

3 June 2021 | | EYE - Cataract, EYE - Refractive | COVID-19, SARS-CoV-2, aerosol-generating procedure, microdroplet generating procedure, phacoemulsification cataract surgery
Half a millilitre of fluorescein was incorporated into 400ml of balanced salt solution to identify microdroplet and splatter from phacoemulsification to simulate possible COVID-19 contamination. Five porcine eyes were mounted to an ophthalmic mannequin head and two surgeons (height 189cm,...

Orbital airgun pellet injuries: A paediatric case pair

10 December 2025 | | EYE - Orbit, EYE - Paediatrics
Airgun injuries to the eye and orbit can be visually devastating. The pellet need not impact the globe directly to cause visual loss, as the cone shaped orbit may funnel the projectile into the orbital apex and optic nerve. We...

The 2020 Milgram Experiment

19 May 2020 | | EYE - General
Will ophthalmology recover from COVID-19? Learning Curve columnist Gwyn Samuel Williams shares his thoughts on the developing impact of the pandemic “It’s busy today,” the nurse in green chuckles. “There are six patients I think.” Six. This clinic is designed...

Optometrist found guilty of manslaughter

1 December 2016 | EYE - General
To start our new Optometry section, editor Janet Pooley takes a look at the tragic death of Vincent Barker and asks what lessons can be learned. In August, Optometrist Honey Rose was found guilty of the manslaughter of eight-year-old Vincent...

Principles of management

1 August 2016 | | EYE - Cataract, EYE - Cornea, EYE - Pathology
Whatever section of pathology is to blame and wherever it strikes, the aim of treatment is always the same. Find the cause if you can. Establish the effects of the cause. Halt the pathological process if you can. Reverse its...

Optical practices to continue to provide urgent and essential care

25 March 2020
The UK Government has now published further guidance clarifying that opticians are exempt from the general requirement for retail businesses and premises to close. Optical practices may therefore continue to provide urgent and essential eye care to the extent that they can, including remote care, while managing COVID-19 risk to keep patients, staff and the public as safe as possible.

Advances and developments in medical retina

1 February 2019 | | EYE - Vitreo-Retinal, EYE - General
The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

3 February 2023 | | EYE - General
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

Life in the glaucoma laboratory

2 October 2025 | | EYE - Glaucoma
When people ask me what life in the laboratory is really like, I often pause. On one hand, it is the romantic notion of pushing back the boundaries of science with the daily rhythm of experiments, data and easily obtained...

Oct/Nov 2018 Quiz

1 October 2018 | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 37-year-old male was referred from the Emergency Eye Clinic with a swollen right upper eyelid. Symptom relieved with nonsteroidal anti-inflammatory drugs (NSAIDs). The initial clinical diagnosis was dacryoadenitis. The patient presented again six weeks later with 3mm proptosis,...