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RaScaL Study

1 June 2015 | | EYE - Vitreo-Retinal
The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...
Ophthalmologica journal front cover image.

Intravitreal Aflibercept (IVT-AFL): treatment of macular oedema secondary to RVO

2 December 2025 | | EYE - Vitreo-Retinal
This paper is a sub-group analysis of the real-world effectiveness, treatment patterns, and safety of IVT-AFL in patients with macular oedema secondary to retinal vein occlusion (RVO) in Italy. One hundred and fifity-two treatment-naïve and 50 pretreated patients were enrolled...

Conference Report: UCL Institute of Ophthalmology Summer School 2025

1 October 2025 | | conference report, meeting, event, training, education
The UCL Institute of Ophthalmology Summer School 2025 was held in collaboration with Moorfields Eye Hospital run by Gordon Hay and Tara Bader. This was a comprehensive five-day course attended by medical students and resident doctors from around the world....

Life’s rich tapestry

2 February 2024 |
Have you ever watched someone cross-stitch, or do needle-point? I recently had the joy of observing my teenage daughter create such an artwork. She separated all the threads into the various colours, and then started to follow the instructions carefully....

Traumatic optic neuropathy

1 October 2021 | | EYE - Orbit, EYE - Neuro-ophthalmology, EYE - General
In neuro-ophthalmology we get asked a lot about management of patients who suffered significant trauma and presented with loss of vision secondary to presumed traumatic optic neuropathy (TON). TON happens usually in the context of significant craniofacial trauma. The incidence...

The results of the last survey Apr24

3 April 2024 | | EYE - General
It has been a few years now since we started these surveys and I continue to be amazed by the variance in our practice. As a patient, I think I would expect there to be more consistency and evidence-based practice....

The results of the last survey Feb25

4 February 2025 | | EYE - Glaucoma, EYE - Vitreo-Retinal, EYE - Cataract
*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. The sample...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

1 February 2017 | | EYE - Vitreo-Retinal
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

In conversation with Robert Henderson

14 November 2024 | EYE - Imaging, EYE - Paediatrics, EYE - Vitreo-Retinal
Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...

Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards

1 December 2018 | | EYE - Vitreo-Retinal, EYE - General
The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...

Neurofibromatosis with multiple bilateral choroidal nevi and literature review

14 November 2024 | | EYE - Imaging, EYE - Oncology, EYE - Vitreo-Retinal
The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...

Proning and the pandemic - ocular complications seen in critical care

6 April 2021 | | EYE - Vitreo-Retinal, EYE - Orbit, EYE - Cornea, EYE - General
Priyanka Sanghi and her co-authors explore the ocular complications seen in critical care units throughout the country as we treat patients through this challenging time. The SARS-Cov-2 (COVID-19) pandemic has placed the NHS and critical care services under immense strain,...