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Quiz Aug/Sep 2025

4 August 2025 | | EYE - Cornea
History A 78-year-old female presented with bilateral, painless, progressive blurring of vision over five years, photophobia and increasing glare. Her past medical history included a known diagnosis of monoclonal gammopathy of undetermined significance (MGUS). On examination, vision in the left...

Essentials of OCT in Ocular Disease

1 October 2016 | | EYE - Imaging, EYE - General
Sir Isaac Newton was the first to establish the technique of low coherence white light interferometry. Following on from this, the principle of laser interferometry as an imaging modality for retina was applied by David Huang and his associates in...

Intravitreal injections delivered by ophthalmic clinical nurse specialists

1 June 2015 | | EYE - Vitreo-Retinal
Intravitreal injections of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab, for the treatment of wet age-related macular degeneration (AMD) was approved by National Institute for Health & Care Excellence (NICE) in 2008 [1]. The Manchester Royal Eye Hospital (MREH),...

Management of proliferative diabetic retinopathy

1 August 2014 | | EYE - Vitreo-Retinal
Diabetic retinopathy is a major cause of blindness in the working-age population. Due to the worsening global epidemic of diabetes, the incidence of morbidity caused by the disease is set to increase [1]. The prevalence of diabetes in the UK...

Efficacy of intravitreal dexamethasone implant in patients with persistent macular oedema

1 December 2014 | | EYE - Vitreo-Retinal
Chronic cystoid macular oedema (CME) can develop secondary to various pathologies such as diabetic maculopathy, retinal vein occlusion and uveitis. It can cause significant visual impairment and macular damage. The therapeutic effect of corticosteroids in CME is through one or...
Ophthalmologica journal cover image.

Effect of syringe-filling technique and risk for endophthalmitis after intravitreal injection of anti-VEGF agents

2 August 2022 | | EYE - Vitreo-Retinal | Aflibercept, Anti-vascular endothelial growth factor, Bevacizumab, Endophthalmitis, Filling, Prefilled syringe, Ranibizumab, Syringe
In this retrospective study the authors compare the risk for post-injection endophthalmitis between different anti-vascular endothelial growth factor (VEGF) agents and syringe preparation technique. This multicentre study included 197,402 injections. The drugs included in this study were three Anti-VEGF agents...
Ophthalmologica journal cover image.

Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection

3 October 2024 | | EYE - Vitreo-Retinal
The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...

Clinical trial investigates ‘Light Touch’ approach to wet AMD treatment

20 October 2025 | NIHR, Treatment, Retina, neovascularisation, vision
A clinical trial led by NIHR Moorfields Clinical Research Facility will explore a new ‘light-touch’ treatment approach for patients with neovascular age-related macular degeneration (wet AMD) that could result in fewer injections and reduced number of clinic visits. Funded by...

The paediatric cataract: an overview of the diagnosis and management

5 August 2020 | | EYE - Cataract, EYE - Refractive, EYE - General
In this second article (see first article here), Samuel Aryee and Rhys Dumont Jones review the challenges involved in managing this condition. Examination and diagnosis Cataracts in children can appear in a variety of forms, each presenting in a different...

Optimising the ocular surface by managing meibomian gland dysfunction

1 February 2016 | | EYE - Cornea
Meibomian gland dysfunction (MGD) is ubiquitous. Ocular surface inflammation and irritation are prevalent in most ophthalmology clinics: corneal, cataract, glaucoma, oculoplastic, paediatric, vitreo-retinal, medical retina and refractive surgery. These patients also represent roughly one third of those attending for emergency...

Clinical and management strategies in glaucoma practice: perspectives from international glaucoma specialists

1 April 2015 | | EYE - Glaucoma
Management options and outcomes in glaucoma practice were reviewed at the 7th Moorfields International Glaucoma Symposium, held in London on 24 January 2015. This article summarises perspectives from international glaucoma specialists on debated issues in topical therapy, glaucoma surgery, diagnostic...

A look into the IOL space

1 October 2014 | | EYE - Cataract, EYE - Refractive
Advances in the design and performance of intraocular lenses (IOLs) continue to be driven by demand for better outcomes, presbyopia correction and spectacle independence, alongside a better understanding of the dynamics of the crystalline lens, newer theories of accommodation and...