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Cementing a VISION 2020 LINK partnership between Blantyre and Liverpool – building capacity for DR services alongside research

Malawi is a small land-locked country in eastern Africa with a growing population of over 17 million people. About 45% of the population is aged 14 or under; only 5% are aged 60 or over. The gross national income per...

Thrombophilia in patients with retinal vein occlusion

The authors present a retrospective study of the prevalence of thrombophilia in patients with retinal vein occlusion. The study cohort included 88 patients with central retinal vein occlusion (CRVO), 51 patients with branch retinal vein occlusion (BRVO) and 40 controls....

Sustainability in eyecare: Intraocular gases and the climate emergency

In 2020 the NHS became the first national health system to commit to delivering ‘net zero’ carbon emissions by 2040. The author investigates how the impact of ophthalmic surgery can be reduced. Medical gases have been used in ophthalmic surgery...

Embryology in clinical practice

The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...

Autophagy in lens mitochondria loss

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Comparison of treatment regimes for APROP

The authors evaluated the risk factors and treatment outcomes of various treatment options for APROP including intra-vitreal anti-VEGF injections, laser treatment and a combination of both. This was an observational study of all consecutive cases of untreated APROP from 2018-19...

Well-presented scholarly research work will reduce chances of journal rebuttal

Submitting to an academic journal? Are you aware of the requirements and constraints of relevant copyright laws? Rod McNeil provides a guide for aspiring authors. Getting published in peer-reviewed academic and medical journals is not easy. But careful attention to...

100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

Ground control to optic nerve – the space oddity to be studied

The authors explore the clinical entity that is known as Spaceflight Associated Neuro-ocular Syndrome (SANS). Its clinical characteristics include optic disc oedema, hyperopic refractive shifts, globe flattening, and chorioretinal folds, may pose a health risk for future space exploration. Understanding...

Leadership and management in optometry: why is it important?

The General Medical Council recognises that leadership and management is essential for every doctor, and provides guidance detailing management and leadership responsibilities [1]. Indeed, management and leadership is part of the core training for all medical trainees. However, to date,...

The role of inflammation in the pathophysiology of DMO

Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Treatment of diabetic macular oedema

Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...