You searched for "outcome"
Direct endoscopic probing for congenital lacrimal duct obstruction
The most common treatment for congenital lacrimal duct obstruction (CLDO) is probing, which is traditionally a blind procedure. Previous literature reports success rates between 78-92%. The authors of this retrospective non comparative case series reviewed the success rates of probing...
PRN Ranibizumab verses continuous aflibercept in UK clinical practice
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...
Moxifloxacin 0.5% for bacterial keratitis
The authors report on the results of a randomised controlled trial comparing commercially available non-preserved moxifloxacin 0.5% vs. a combination of fortified cefazolin 5% and tobramycin 1.3% in the treatment of moderate bacterial keratitis without perforation. Corneal scrapings were collected...
Features of Behcet’s disease
This is a retrospective single centre study from Paris, France, between the periods of 1986 to 2015. Twenty-nine out of 217 (13.3%) neuro-Behcet’s disease (NBD) patients presented with neuro-ophthalmic manifestations (55% of men and mean age of 28 years). Sixteen...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
Clinicopathologic factors and survival in patients with sebaceous carcinoma of eyelid
This is a population-based analysis performed to evaluate the prognostic factors and survival of patients with sebaceous carcinoma of the eyelid. Patients with eyelid sebaceous carcinoma from 1973-2013 were identified from the Surveillance, Epidemiology and End Results (SEER) database and...
Oculofacial plastic surgery – is antibiotic prophylaxis required?
This is a randomised, controlled, unmasked clinical trial evaluating whether topical antibiotic prophylaxis reduces the rate of infection after oculofacial plastic surgery compared to a non-antibiotic ointment. A total of 401 participants over the age of 18 were recruited, with...
One-week intubation in external dacryocystorhinostomy
Whether to routinely intubate or not in dacryocystorhinostomy (DCR) surgery has been a subject of controversy among lacrimal surgeons. Similarly, if intubated the timing of removal of stent is not standard. Here, the authors carried out a survey of their...
G-CSF intravitreal injections for NAION: a pilot study
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...
Management and outcomes of congenital fibrovascular pupillary membranes (CFPM)
Congenital fibrovascular pupillary membranes (CFPM) is defined as a white fibrous membrane across the pupil which may be an ectopic iris tissue arising from the aberrant migration of neural crest cells or a variant of persistent fetal vasculature. The authors...
Needling procedure for failed bleb
The aim of this study was to determine the efficacy of needling with 5-FU after failed filtering procedures in the paediatric population. This was a retrospective review of 324 filtration surgeries in 265 children with 55 eyes (16.9%) undergoing needling...
