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Prostaglandin-associated periorbitopathy
This is a masked study of 33 patients who had been taking a prostaglandin analogue in one eye only for at least a year, to look for signs of prostaglandin-associated periorbitopathy (PAP). The investigators devised a new grading system to...
A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model
This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...
Sex differences in the relationship between obesity and choroidal nevus in US adults
The National Health and Nutrition Examination Survey (NHANES); a population-based survey conducted annually in the US by the Centers for Disease Control and Prevention, was used to identify populations at higher risk for choroidal naevus. Over a period of four...
Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
Platelet-rich fibrin for conjunctivoplasty after pterygium excision
The authors report a prospective, comparative, non-randomized clinical trial of 35 pterygium patients with unilateral nasal primary pterygium infiltrating the cornea 2-5mm in size, who underwent pterygium excision between June 2013 and September 2014. Thirty-five eyes of 35 patients with...
Ologen Collagen Matrix to treat ocular hypotony after filtration glaucoma surgery
The authors report a retrospective, observational case series of a Japanese cohort. 12 consecutive implantations of ologen in nine eyes of nine subjects (five men, four women; mean age ±SD, 72.1±12.7 years) who underwent subconjunctival implantation of the device to...
Development of testing protocols for high and low contrast visual acuity
Dysfunction of the afferent visual system, characterised by impairments in high-contrast visual acuity (HCVA) and low-contrast visual acuity (LCVA) have been demonstrated in some neurological conditions such as multiple sclerosis and Parkinson’s disease. HCVA and LCVA are also potential quantitative...
OCT measures of lateral and medial recti
The authors assessed the agreement of the measurements of the horizontal rectus muscle insertion distance to the limbus and the muscle thickness between three different OCT devices. This was a cross section observation study of 70 eyes of 35 subjects....
IAC vs. IVC chemotherapy for RB
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
Subfoveal choroidal thickness and PCV
This report studies the prognostic factors for visual improvement and the need for additional treatments at one year after the initial combination therapy of intravitreal ranibizumab injection or intravitreal aflibercept injection followed by PDT in eyes with PCV. Fifty-six eyes...
Systemic pharmacology of intravitreal anti-VEGF
This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...
