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Ophthalmology in the developing world

After the second year of medical school, I spent my summer vacation working as a volunteer for a small Italian non-government organisation (NGO), named HEALTH-AID. As part of my volunteering experience, I joined a team of European doctors, medical students...

Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD

This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...

Efficacy of intravitreal dexamethasone implant in patients with persistent macular oedema

Chronic cystoid macular oedema (CME) can develop secondary to various pathologies such as diabetic maculopathy, retinal vein occlusion and uveitis. It can cause significant visual impairment and macular damage. The therapeutic effect of corticosteroids in CME is through one or...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

Long-term outcomes of intravitreal ranibizumab for neovascular AMD

This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...

Endophthalmitis after intravitreal injections in France

In this nationwide, retrospective, multicentre case series, the authors looked at the incidence and characteristics of endophthalmitis after intravitreal injections of anti-VEGFs and steroids, given for a variety of posterior segment conditions (macular oedema secondary to diabetes or retinal vein...

One-year result of XEN45 implant for glaucoma: efficacy, safety, and postoperative management

The authors report a retrospective, non-randomised interventional case series of 39 patients who underwent a standalone XEN45 implantation. All 39 patients (female: male=1.2: 1) completed 12-month follow-up. Mean age was 70.1 years (range 32–92). Primary outcome measures were the intraocular...

Microbial keratitis in corneal grafts

The authors report a retrospective case series of 59 episodes of microbial keratitis identified in 41 eyes of 41 patients (39 penetrating keratoplasty (PKPs) and two deep anterior lamellar keratoplasty (DALKs)), from a total of 759 consecutive corneal grafts identified...

Mono vs. multi-therapy in IOP control

This randomised control trial studied newly diagnosed glaucoma patients given mono‐ or multi‐therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction. Patients newly diagnosed with manifest primary...

Intravitreal Bevacizumab for the prevention of postoperative proliferative vitreoretinopathy in high-risk patients

This single- centre observational retrospective study was conducted to evaluate the effect of intravitreal injection of bevacizumab at the time surgery for rhegmatogenous retinal detachment (RRD) repair on postoperative proliferative vitreoretinopathy (PVR) in patients at high risk selected by laser...

Autofluorescence patterns in subretinal haemorrhages associated with neovascular age-related macular degeneration

The aim of this retrospective study was to describe the surgical results and fundus autofluorescence (FAF) patterns occurring in sub-macular haemorrhage (SMH) of duration <60 days in age-related macular degeneration (AMD). Notes from 39 eyes of 39 patients with SMH,...

Report: National Student Ophthalmology Conference 2023

A report covering the NSOC23 event which took place on 25 March 2023.