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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Sustainability in eyecare: Climate action in eyecare

4 August 2021 | | EYE - General
Climate change will cause disruption to critical eyecare services and increases in rates of eye disease around the world. The International Agency for Prevention of Blindness has recommended 10 key areas of action on how the eyecare sector can address...

ChatGPT cannot pass FRCOphth examinations: implications for ophthalmology and large language model artificial intelligence

26 April 2023 | | EYE - General
Large language models are generating a lot of hype for artificial intelligence, but can they assist patients and practitioners in ophthalmology? Introduction Deep learning (DL) has emerged in ophthalmology as an exciting form of artificial intelligence (AI) most commonly applied...

Blinded by an Ofsted inspection

7 December 2023 | | EYE - General
Introduction The Association of Health Professions in Ophthalmology (AHPO) is a charity, whose objectives are to promote the practice, education, training and research in ophthalmology and vision science in the UK. The extraordinary developments in diagnostic equipment and technologies have...

Clinical relevance of the anatomic classification of neovascular age-related macular degeneration

1 February 2018 | | EYE - Imaging, EYE - Vitreo-Retinal
The author explains why an OCT-based classification of neovascular AMD is needed and how these neovascular subtypes may help to predict patients’ long-term visual outcome. Age-related macular degeneration (AMD) is a chronic and progressive neurodegenerative process involving the macula in...

Strabismus and ocular motility, demystified

3 April 2024 | | EYE - Paediatrics, EYE - Strabismus, EYE - General
I am a former orthoptist, now trained in medicine and working as a foundation doctor. In my previous work, I was frequently approached by ophthalmology trainees eager for guidance with strabismus and ocular motility. Drawing on my clinical experience, I...

Binocular single vision (BSV)

3 April 2023 | | EYE - General
Introduction In this article I will try to summarise some of the definitions, tests and assessments performed in the strabismus clinic to assess patient binocular potential. This is a key feature of strabismus assessment, especially in adults, and it will...

Herpes zoster ophthalmicus: a clinician’s perspective

25 January 2023 | | EYE - General
Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

Brave new world

3 June 2024 |
It’s a great honour to be handed the editorial relay baton by Professor Bal Dhillon and I hope I don’t fumble it along the way. As I put pen to paper, I reflect on Bal’s signing off in the last...

The management of chronic central serous chorioretinopathy

1 February 2017 | | EYE - Vitreo-Retinal
Central serous chorioretinopathy (CSCR) is a common retinal disease characterised by one or more serous neurosensory detachments. Patients present with acute onset blurring of vision, metamorphopsia and / or central scotomas. The condition is six times more common in men...

Cataract surgery in uveitis patients

1 February 2016 | | EYE - Cataract, EYE - Refractive
Cataract formation is a common complication of uveitis, causing up to 40% of vision loss in these patients. Cataract results from inflammation +/- corticosteroid therapy and is usually posterior subcapsular, but a small proportion have a rapid increase in nuclear...

How to diagnose and treat Acanthamoeba keratitis

1 February 2019 | | EYE - Cornea, EYE - General
Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...